About Zinc finger protein 236
Zinc finger protein 236 (ZNF236) is a protein
from Homo sapiens identified by UniProt accession
Q9UL36, 1845 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | Zinc finger protein 236 |
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| UniProt accession | Q9UL36 |
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| Gene | ZNF236 |
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| Organism | Homo sapiens |
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| Length | 1845 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (55)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.45
- prostate carcinoma · score 0.33
- HbA1c measurement · score 0.33
- hemoglobin A1 measurement · score 0.32
- FEV/FVC ratio · score 0.25
- red blood cell density measurement · score 0.23
- neuroimaging measurement · score 0.22
- brain volume measurement · score 0.22
- lymphedema · score 0.18
- gastric carcinoma · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UL36-F1 | alphafold | PREDICTED | 54.03 | — |
Amino-acid sequence (1845 residues)
MGLCGLLERC WLHHDPDGVL TLNAENTNYA YQVPNFHKCE ICLLSFPKES QFQRHMRDHE RNDKPHRCDQ CPQTFNVEFN LTLHKCTHSG EDPTCPVCNK KFSRVASLKA HIMLHEKEEN LICSECGDEF TLQSQLAVHM EEHRQELAGT RQHACKACKK EFETSSELKE HMKTHYKIRV SSTRSYNRNI DRSGFTYSCP HCGKTFQKPS QLTRHIRIHT GERPFKCSEC GKAFNQKGAL QTHMIKHTGE KPHACAFCPA AFSQKGNLQS HVQRVHSEVK NGPTYNCTEC SCVFKSLGSL NTHISKMHMG GPQNSTSSTE TAHVLTATLF QTLPLQQTEA QATSASSQPS SQAVSDVIQQ LLELSEPAPV ESGQSPQPGQ QLSITVGINQ DILQQALENS GLSSIPAAAH PNDSCHAKTS APHAQNPDVS SVSNEQTDPT DAEQEKEQES PEKLDKKEKK MIKKKSPFLP GSIREENGVR WHVCPYCAKE FRKPSDLVRH IRIHTHEKPF KCPQCFRAFA VKSTLTAHIK THTGIKAFKC QYCMKSFSTS GSLKVHIRLH TGVRPFACPH CDKKFRTSGH RKTHIASHFK HTELRKMRHQ RKPAKVRVGK TNIPVPDIPL QEPILITDLG LIQPIPKNQF FQSYFNNNFV NEADRPYKCF YCHRAYKKSC HLKQHIRSHT GEKPFKCSQC GRGFVSAGVL KAHIRTHTGL KSFKCLICNG AFTTGGSLRR HMGIHNDLRP YMCPYCQKTF KTSLNCKKHM KTHRYELAQQ LQQHQQAASI DDSTVDQQSM QASTQMQVEI ESDELPQTAE VVAANPEAML DLEPQHVVGT EEAGLGQQLA DQPLEADEDG FVAPQDPLRG HVDQFEEQSP AQQSFEPAGL PQGFTVTDTY HQQPQFPPVQ QLQDSSTLES QALSTSFHQQ SLLQAPSSDG MNVTTRLIQE SSQEELDLQA QGSQFLEDNE DQSRRSYRCD YCNKGFKKSS HLKQHVRSHT GEKPYKCKLC GRGFVSSGVL KSHEKTHTGV KAFSCSVCNA SFTTNGSLTR HMATHMSMKP YKCPFCEEGF RTTVHCKKHM KRHQTVPSAV SATGETEGGD ICMEEEEEHS DRNASRKSRP EVITFTEEET AQLAKIRPQE SATVSEKVLV QSAAEKDRIS ELRDKQAELQ DEPKHANCCT YCPKSFKKPS DLVRHVRIHT GEKPYKCDEC GKSFTVKSTL DCHVKTHTGQ KLFSCHVCSN AFSTKGSLKV HMRLHTGAKP FKCPHCELRF RTSGRRKTHM QFHYKPDPKK ARKPMTRSSS EGLQPVNLLN SSSTDPNVFI MNNSVLTGQF DQNLLQPGLV GQAILPASVS AGGDLTVSLT DGSLATLEGI QLQLAANLVG PNVQISGIDA ASINNITLQI DPSILQQTLQ QGNLLAQQLT GEPGLAPQNS SLQTSDSTVP ASVVIQPISG LSLQPTVTSA NLTIGPLSEQ DSVLTTNSSG TQDLTQVMTS QGLVSPSGGP HEITLTINNS SLSQVLAQAA GPTATSSSGS PQEITLTISE LNTTSGSLPS TTPMSPSAIS TQNLVMSSSG VGGDASVTLT LADTQGMLSG GLDTVTLNIT SQGQQFPALL TDPSLSGQGG AGSPQVILVS HTPQSASAAC EEIAYQVAGV SGNLAPGNQP EKEGRAHQCL ECDRAFSSAA VLMHHSKEVH GRERIHGCPV CRKAFKRATH LKEHMQTHQA GPSLSSQKPR VFKCDTCEKA FAKPSQLERH SRIHTGERPF HCTLCEKAFN QKSALQVHMK KHTGERPYKC AYCVMGFTQK SNMKLHMKRA HSYAGALQES AGHPEQDGEE LSRTLHLEEV VQEAAGEWQA LTHVF
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