About Zinc finger protein 346
Zinc finger protein 346 (ZNF346) is a protein
from Homo sapiens identified by UniProt accession
Q9UL40, 294 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | Zinc finger protein 346 |
|---|
| UniProt accession | Q9UL40 |
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| Gene | ZNF346 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 294 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (37)
Diseases linked to this target (Open Targets).
- age at menopause · score 0.09
- uterine fibroid · score 0.08
- hepatocellular carcinoma · score 0.07
- self reported educational attainment · score 0.07
- menopause · score 0.06
- age at menarche · score 0.05
- hypertriglyceridemia 2 · score 0.05
- cholesterol-ester transfer protein deficiency · score 0.05
- neuroblastoma · score 0.05
- mathematical ability · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UL40-F1 | alphafold | PREDICTED | 66.52 | — |
Amino-acid sequence (294 residues)
MEYPAPATVQ AADGGAAGPY SSSELLEGQE PDGVRFDRER ARRLWEAVSG AQPVGREEVE HMIQKNQCLF TNTQCKVCCA LLISESQKLA HYQSKKHANK VKRYLAIHGM ETLKGETKKL DSDQKSSRSK DKNQCCPICN MTFSSPVVAQ SHYLGKTHAK NLKLKQQSTK VEALHQNREM IDPDKFCSLC HATFNDPVMA QQHYVGKKHR KQETKLKLMA RYGRLADPAV TDFPAGKGYP CKTCKIVLNS IEQYQAHVSG FKHKNQSPKT VASSLGQIPM QRQPIQKDST TLED
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