Zinc finger protein 215 (ZNF215)

About Zinc finger protein 215

Zinc finger protein 215 (ZNF215) is a protein from Homo sapiens identified by UniProt accession Q9UL58, 517 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Zinc finger protein 215
UniProt accession	Q9UL58
Gene	ZNF215
Organism	Homo sapiens
Length	517 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

acute myeloid leukemia · score 0.02
blood protein measurement · score 0.02
cancer · score 0.02
Beckwith-Wiedemann syndrome · score 0.01
periodontitis · score 0.01
neoplasm · score 0.01
triple-negative breast cancer · score 0.01
genetic disorder · score 0.01
chronic obstructive pulmonary disease · score 0.00
cryptorchidism · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UL58-F1	alphafold	PREDICTED	49.30	—

Amino-acid sequence (517 residues)

MQPLSKLMAI SKPRNLSLRE QREVLRADMS WQQETNPVVE THDSEASRQK FRHFQYLKVS GPHEALSQLW ELCLQWLRPE IHTKKQIIEL LVLEQFLAIL PEEVRTWVNL QHPNNSKDMV TLIEDVIEML EDEDMPCKDS ALQMGSIKEK MKAGSRTGKP QEPVTFKDVV VEFSKEEWGQ LDSAVKNLYR NVMLENFRNL NSLRKAHLLS KPFESLKLES KKKRWIMEKE IPRKTIFDMK SISGEESSHG VIMTRLTESG HPSSDAWKGE NWLYRNQKKW DINLPQEAFI PETIYTEEED FECSENKKSF DINSVSSICA IQVGIPSRKG SPKCDKFKTY FKFNLDSVGK QHSEYEYGND LSLSTDIRHQ KSHTTMNSYE CYQCGKAFCR SSSLIRHQII HTGEKPYKCS ECGRFFNRRT NLTKHQKLHA EAKACTSNKC GKAFSKSEDS NNPTLHFGNN FYQCVNCGKS FNRSSSLIRH QMIHTGEKPF KCKECSKAFN RSSNLVKHQK LHTRDKS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards