About Proline-rich protein 12
Proline-rich protein 12 (PRR12) is a protein
from Homo sapiens identified by UniProt accession
Q9ULL5, 2036 residues long.
MolForge cross-references it against 0 known binders and
58 disease associations.
Target properties
| Protein name | Proline-rich protein 12 |
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| UniProt accession | Q9ULL5 |
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| Gene | PRR12 |
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| Organism | Homo sapiens |
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| Length | 2036 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9ULL5-F1 | alphafold | PREDICTED | 42.76 | — |
Amino-acid sequence (2036 residues)
MDRNYPSAGF GDPLGAGAGW SYERSAKASL VYGSSRTSHP ETDILHRQAY AAPHPLQSYA TNHHPAGLSG LFDTGLHHAG SAGPDASVMN LISALESRGP QPGPSASSLL SQFRSPSWQT AMHTPGPTEL FISGALPGSS TFPSSSALSA YQHPASFGSR PFPVPSSLSL QDPPFSPPAN GLLSPHDVLH LKPSQAPTVP SSLGFERLAG GGVLGPAGLG PAQTPPYRPG PPDPPPPPRH LPTQFNLLAS SSAAAAAAEQ SSPQLYNFSG AAPGPPPPER ALPRQDTVIK HYQRPASAQP PPPPPPAHAL QHYLSCGGSY PSMGHRANLA CSPLGGGEPS PGAGEPSKAG PSGATAGASG RATGPEAAGG GGAGGGGGGY RPIIQSPGYK TGKGGYGAAA GGATRPPPPR STATPKCQSL GGPAAAYATG KASGAGGAGG QAYSPGQPQG LLGPQAYGQG FGGGQAQDLS KAPSYSGGPP QPPSGPPPPG LATCQSYSPD QLQGQLYGVQ GEPYPGPAAH SQGLPTASPS LSYSTGHSPA LSGHGGGWGP SSLGGGGEAS PSHIIRPLQS PPATGRPPGV GSPGAPGKYL SSVLASAPFL APPGAGSYAA GAGGYKGKGD GSELLAGPGG PPAERTEDEE FLIQHLLQAP SPPRTSGADG LVGEDGAADA SKGLGGSGGA GGPPGTPYEL AKEDPQRYHL QSVIRTSASL DEGATAALEL GLGRLKEKKK GPERGGETPE GLATSVVHYG AGAKELGAFL QKSPPPPPPT AQSTQPTPHG LLLEAGGPDL PLVLPPPPPQ LLPSVLSHAP SPSPSASKVG VHLLEPATRD GAPQPPPPPP PPPPPMPLQL EAHLRSHGLE PAAPSPRLRP EESLDPPGAM QELLGALEPL PPAPGDTGVG PPNSEGKDPA GAYRSPSPQG TKAPRFVPLT SICFPDSLLQ DEERSFFPTM EEMFGGGAAD DYGKAGPPED EGDPKAGAGP PPGPPAYDPY GPYCPGRASG AGPETPGLGL DPNKPPELPS TVNAEPLGLI QSGPHQAAPP PPPPPPPPPA PASEPKGGLT SPIFCSTKPK KLLKTSSFHL LRRRDPPFQT PKKLYAQEYE FEADEDKADV PADIRLNPRR LPDLVSSCRS RPALSPLGDI DFCPPNPGPD GPRRRGRKPT KAKRDGPPRP RGRPRIRPLE VPTTAGPASA STPTDGAKKP RGRGRGRGRK AEEAGGTRLE PLKPLKIKLS VPKAGEGLGT SSGDAISGTD HNSLDSSLTR EKIEAKIKEV EEKQPEMKSG FMASFLDFLK SGKRHPPLYQ AGLTPPLSPP KSVPPSVPAR GLQPQPPATP AVPHPPPSGA FGLGGALEAA ESEGLGLGCP SPCKRLDEEL KRNLETLPSF SSDEEDSVAK NRDLQESISS AISALDDPPL AGPKDTSTPD GPPLAPAAAV PGPPPLPGLP SANSNGTPEP PLLEEKPPPT PPPAPTPQPQ PPPPPPPPQP ALPSPPPLVA PTPSSPPPPP LPPPPPPAMP SPPPPPPPAA APLAAPPEEP AAPSPEDPEL PDTRPLHLAK KQETAAVCGE TDEEAGESGG EGIFRERDEF VIRAEDIPSL KLALQTGREP PPIWRVQKAL LQKFTPEIKD GQRQFCATSN YLGYFGDAKN RYQRLYVKFL ENVNKKDYVR VCARKPWHRP PVPVRRSGQA KNPVSAGGSS APPPKAPAPP PKPETPEKTT SEKPPEQTPE TAMPEPPAPE KPSLLRPVEK EKEKEKVTRG ERPLRGERAT SGRQTRPERS LATGQPATSR LPKARPTKVK AEPPPKKRKK WLKEAGGNAT AGGGPPGSSS DSESSPGAPS EDERAVPGRL LKTRAMREMY RSYVEMLVST ALDPDMIQAL EDTHDELYLP PMRKIDGLLN EHKKKVLKRL SLSPALQDAL HTFPQLQVEQ SGEGSPEEGA VRLRPAGEPY NRKTLSKLKR SVVRAQEFKV ELEKSGYYTL YHSLHHYKYH TFLRCRDQTL AIEGGAEDLG QEEVVQQCMR NQPWLEQLFD SFSDLLAQAQ AHSRCG
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