About Protein NDRG4
Protein NDRG4 (NDRG4) is a protein
from Homo sapiens identified by UniProt accession
Q9ULP0, 352 residues long.
MolForge cross-references it against 0 known binders and
103 disease associations.
Target properties
| Protein name | Protein NDRG4 |
|---|
| UniProt accession | Q9ULP0 |
|---|
| Gene | NDRG4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 352 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (103)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.38
- sex hormone-binding globulin measurement · score 0.19
- TPE interval measurement · score 0.19
- schizophrenia · score 0.16
- Hepatoblastoma · score 0.11
- neoplasm · score 0.10
- platelet count · score 0.10
- erythrocyte count · score 0.09
- alkaline phosphatase measurement · score 0.09
- QT interval · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9ULP0-F1 | alphafold | PREDICTED | 84.48 | — |
Amino-acid sequence (352 residues)
MPECWDGEHD IETPYGLLHV VIRGSPKGNR PAILTYHDVG LNHKLCFNTF FNFEDMQEIT KHFVVCHVDA PGQQVGASQF PQGYQFPSME QLAAMLPSVV QHFGFKYVIG IGVGAGAYVL AKFALIFPDL VEGLVLVNID PNGKGWIDWA ATKLSGLTST LPDTVLSHLF SQEELVNNTE LVQSYRQQIG NVVNQANLQL FWNMYNSRRD LDINRPGTVP NAKTLRCPVM LVVGDNAPAE DGVVECNSKL DPTTTTFLKM ADSGGLPQVT QPGKLTEAFK YFLQGMGYIA YLKDRRLSGG AVPSASMTRL ARSRTASLTS ASSVDGSRPQ ACTHSESSEG LGQVNHTMEV SC
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