About Frizzled-10
Frizzled-10 (FZD10) is a protein
from Homo sapiens identified by UniProt accession
Q9ULW2, 581 residues long.
MolForge cross-references it against 0 known binders and
74 disease associations.
Target properties
| Protein name | Frizzled-10 |
|---|
| UniProt accession | Q9ULW2 |
|---|
| Gene | FZD10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 581 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (74)
Diseases linked to this target (Open Targets).
- balding measurement · score 0.34
- androgenetic alopecia · score 0.32
- cortical thickness · score 0.32
- hair shape measurement · score 0.32
- cortical surface area measurement · score 0.31
- neurodegenerative disease · score 0.30
- Myopia · score 0.26
- alopecia · score 0.25
- brain measurement · score 0.25
- urate measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9ULW2-F1 | alphafold | PREDICTED | 80.64 | — |
Amino-acid sequence (581 residues)
MQRPGPRLWL VLQVMGSCAA ISSMDMERPG DGKCQPIEIP MCKDIGYNMT RMPNLMGHEN QREAAIQLHE FAPLVEYGCH GHLRFFLCSL YAPMCTEQVS TPIPACRVMC EQARLKCSPI MEQFNFKWPD SLDCRKLPNK NDPNYLCMEA PNNGSDEPTR GSGLFPPLFR PQRPHSAQEH PLKDGGPGRG GCDNPGKFHH VEKSASCAPL CTPGVDVYWS REDKRFAVVW LAIWAVLCFF SSAFTVLTFL IDPARFRYPE RPIIFLSMCY CVYSVGYLIR LFAGAESIAC DRDSGQLYVI QEGLESTGCT LVFLVLYYFG MASSLWWVVL TLTWFLAAGK KWGHEAIEAN SSYFHLAAWA IPAVKTILIL VMRRVAGDEL TGVCYVGSMD VNALTGFVLI PLACYLVIGT SFILSGFVAL FHIRRVMKTG GENTDKLEKL MVRIGLFSVL YTVPATCVIA CYFYERLNMD YWKILAAQHK CKMNNQTKTL DCLMAASIPA VEIFMVKIFM LLVVGITSGM WIWTSKTLQS WQQVCSRRLK KKSRRKPASV ITSGGIYKKA QHPQKTHHGK YEIPAQSPTC V
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