About Hippocalcin-like protein 4
Hippocalcin-like protein 4 (HPCAL4) is a protein
from Homo sapiens identified by UniProt accession
Q9UM19, 191 residues long.
MolForge cross-references it against 0 known binders and
44 disease associations.
Target properties
| Protein name | Hippocalcin-like protein 4 |
|---|
| UniProt accession | Q9UM19 |
|---|
| Gene | HPCAL4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 191 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (44)
Diseases linked to this target (Open Targets).
- antisocial behaviour measurement · score 0.24
- substance abuse · score 0.24
- attention deficit hyperactivity disorder · score 0.24
- medulloblastoma · score 0.05
- dacryocystitis-osteopoikilosis syndrome · score 0.05
- melorheostosis · score 0.05
- heel bone mineral density · score 0.04
- 12q14 microdeletion syndrome · score 0.04
- pyknoachondrogenesis · score 0.04
- astrocytoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UM19-F1 | alphafold | PREDICTED | 86.34 | — |
Amino-acid sequence (191 residues)
MGKTNSKLAP EVLEDLVQNT EFSEQELKQW YKGFLKDCPS GILNLEEFQQ LYIKFFPYGD ASKFAQHAFR TFDKNGDGTI DFREFICALS VTSRGSFEQK LNWAFEMYDL DGDGRITRLE MLEIIEAIYK MVGTVIMMRM NQDGLTPQQR VDKIFKKMDQ DKDDQITLEE FKEAAKSDPS IVLLLQCDMQ K
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