About Mammalian ependymin-related protein 1
Mammalian ependymin-related protein 1 (EPDR1) is a protein
from Homo sapiens identified by UniProt accession
Q9UM22, 224 residues long.
MolForge cross-references it against 0 known binders and
99 disease associations.
Target properties
| Protein name | Mammalian ependymin-related protein 1 |
|---|
| UniProt accession | Q9UM22 |
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| Gene | EPDR1 |
|---|
| Organism | Homo sapiens |
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| Length | 224 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (99)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.25
- blood protein measurement · score 0.25
- bone quantitative ultrasound measurement · score 0.24
- body height · score 0.24
- Dupuytren Contracture · score 0.24
- Fasciitis · score 0.21
- Palmar Fibromatosis · score 0.21
- bone density · score 0.19
- frozen shoulder · score 0.14
- refractive error measurement · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UM22-F1 | alphafold | PREDICTED | 85.88 | — |
Amino-acid sequence (224 residues)
MPGRAPLRTV PGALGAWLLG GLWAWTLCGL CSLGAVGAPR PCQAPQQWEG RQVMYQQSSG RNSRALLSYD GLNQRVRVLD ERKALIPCKR LFEYILLYKD GVMFQIDQAT KQCSKMTLTQ PWDPLDIPQN STFEDQYSIG GPQEQITVQE WSDRKSARSY ETWIGIYTVK DCYPVQETFT INYSVILSTR FFDIQLGIKD PSVFTPPSTC QMAQLEKMSE DCSW
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