NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1)

About NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) is a protein from Homo sapiens identified by UniProt accession Q9UMS0, 254 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.

Target properties

Protein name	NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
UniProt accession	Q9UMS0
Gene	NFU1
Organism	Homo sapiens
Length	254 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UMS0-F1	alphafold	PREDICTED	78.92	—

Amino-acid sequence (254 residues)

MAATARRGWG AAAVAAGLRR RFCHMLKNPY TIKKQPLHQF VQRPLFPLPA AFYHPVRYMF IQTQDTPNPN SLKFIPGKPV LETRTMDFPT PAAAFRSPLA RQLFRIEGVK SVFFGPDFIT VTKENEELDW NLLKPDIYAT IMDFFASGLP LVTEETPSGE AGSEEDDEVV AMIKELLDTR IRPTVQEDGG DVIYKGFEDG IVQLKLQGSC TSCPSSIITL KNGIQNMLQF YIPEVEGVEQ VMDDESDEKE ANSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards