About Sex comb on midleg-like protein 1
Sex comb on midleg-like protein 1 (SCML1) is a protein
from Homo sapiens identified by UniProt accession
Q9UN30, 329 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Sex comb on midleg-like protein 1 |
|---|
| UniProt accession | Q9UN30 |
|---|
| Gene | SCML1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 329 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- colorectal cancer · score 0.02
- Nephroblastoma · score 0.02
- Sepsis · score 0.01
- Pick disease · score 0.01
- IGA glomerulonephritis · score 0.00
- breast carcinoma · score 0.00
- hepatocellular carcinoma · score 0.00
- meningococcal infection · score 0.00
- Alzheimer disease · score 0.00
- metastatic melanoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UN30-F1 | alphafold | PREDICTED | 66.85 | — |
Amino-acid sequence (329 residues)
MMSNSSSEID VIKTRIPTYD EDDNTILYAY ETKPEFVNKE PNIVSDASCN TEEQLKTVDD VLIHCQVIYD ALQNLDKKID VIRRKVSKIQ RFHARSLWTN HKRYGYKKHS YRLVKKLKLQ KMKKNEVYET FSYPESYSPT LPVSRRENNS PSNLPRPSFC MEEYQRAELE EDPILSRTPS PVHPSDFSEH NCQPYYASDG ATYGSSSGLC LGNPRADSIH NTYSTDHASA APPSVTRSPV ENDGYIEEGS ITKHPSTWSV EAVVLFLKQT DPLALCPLVD LFRSHEIDGK ALLLLTSDVL LKHLGVKLGT AVKLCYYIDR LKQGKCFEN
Explore Sex comb on midleg-like protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets