About Protein NDRG2
Protein NDRG2 (NDRG2) is a protein
from Homo sapiens identified by UniProt accession
Q9UN36, 371 residues long.
MolForge cross-references it against 0 known binders and
282 disease associations.
Target properties
| Protein name | Protein NDRG2 |
|---|
| UniProt accession | Q9UN36 |
|---|
| Gene | NDRG2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 371 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (282)
Diseases linked to this target (Open Targets).
- body height · score 0.24
- appendicular lean mass · score 0.22
- protein measurement · score 0.17
- amino acid measurement · score 0.17
- blood metabolite measurement · score 0.17
- lean body mass · score 0.15
- fat body mass · score 0.12
- neoplasm · score 0.12
- urticaria · score 0.11
- hepatocellular carcinoma · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UN36-F1 | alphafold | PREDICTED | 83.60 | — |
Amino-acid sequence (371 residues)
MAELQEVQIT EEKPLLPGQT PEAAKEAELA ARILLDQGQT HSVETPYGSV TFTVYGTPKP KRPAILTYHD VGLNYKSCFQ PLFQFEDMQE IIQNFVRVHV DAPGMEEGAP VFPLGYQYPS LDQLADMIPC VLQYLNFSTI IGVGVGAGAY ILARYALNHP DTVEGLVLIN IDPNAKGWMD WAAHKLTGLT SSIPEMILGH LFSQEELSGN SELIQKYRNI ITHAPNLDNI ELYWNSYNNR RDLNFERGGD ITLRCPVMLV VGDQAPHEDA VVECNSKLDP TQTSFLKMAD SGGQPQLTQP GKLTEAFKYF LQGMGYMASS CMTRLSRSRT ASLTSAASVD GNRSRSRTLS QSSESGTLSS GPPGHTMEVS C
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