About Translocon-associated protein subunit gamma
Translocon-associated protein subunit gamma (SSR3) is a protein
from Homo sapiens identified by UniProt accession
Q9UNL2, 185 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | Translocon-associated protein subunit gamma |
|---|
| UniProt accession | Q9UNL2 |
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| Gene | SSR3 |
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| Organism | Homo sapiens |
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| Length | 185 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (37)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- congenital disorder of glycosylation · score 0.32
- Testicular Germ Cell Tumor · score 0.25
- protein measurement · score 0.24
- body mass index · score 0.22
- blood phosphate measurement · score 0.21
- chronic obstructive pulmonary disease · score 0.19
- visceral adipose tissue measurement · score 0.17
- endometrial cancer · score 0.11
- heel bone mineral density · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UNL2-F1 | alphafold | PREDICTED | 84.46 | — |
Amino-acid sequence (185 residues)
MAPKGSSKQQ SEEDLLLQDF SRNLSAKSSA LFFGNAFIVS AIPIWLYWRI WHMDLIQSAV LYSVMTLVST YLVAFAYKNV KFVLKHKVAQ KREDAVSKEV TRKLSEADNR KMSRKEKDER ILWKKNEVAD YEATTFSIFY NNTLFLVVVI VASFFILKNF NPTVNYILSI SASSGLIALL STGSK
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