Zinc finger protein 232 (ZNF232)

About Zinc finger protein 232

Zinc finger protein 232 (ZNF232) is a protein from Homo sapiens identified by UniProt accession Q9UNY5, 444 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Zinc finger protein 232
UniProt accession	Q9UNY5
Gene	ZNF232
Organism	Homo sapiens
Length	444 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

family history of Alzheimer’s disease · score 0.07
platelet component distribution width · score 0.07
mean platelet volume · score 0.05
lymphocyte count · score 0.05
late-onset Alzheimers disease · score 0.03
sum of neutrophil and eosinophil counts · score 0.02
myeloid white cell count · score 0.02
body height · score 0.02
Alzheimer disease · score 0.02
hepatocellular carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UNY5-F1	alphafold	PREDICTED	60.34	—

Amino-acid sequence (444 residues)

MEPPGPVRGP LQDSSWYEPS AELVQTRMAV SLTAAETLAL QGTQGQEKMM MMGPKEEEQS CEYETRLPGN HSTSQEIFRQ RFRHLRYQET PGPREALSQL RVLCCEWLRP EKHTKEQILE FLVLEQFLTI LPEELQSWVR GHHPKSGEEA VTVLEDLEKG LEPEPQVPGP AHGPAQEEPW EKKESLGAAQ EALSIQLQPK ETQPFPKSEQ VYLHFLSVVT EDGPEPKDKG SLPQPPITEV ESQVFSEKLA TDTSTFEATS EGTLELQQRN PKAERLRWSP AQEESFRQMV VIHKEIPTGK KDHECSECGK TFIYNSHLVV HQRVHSGEKP YKCSDCGKTF KQSSNLGQHQ RIHTGEKPFE CNECGKAFRW GAHLVQHQRI HSGEKPYECN ECGKAFSQSS YLSQHRRIHS GEKPFICKEC GKAYGWCSEL IRHRRVHARK EPSH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards