NSFL1 cofactor p47 (NSFL1C)

About NSFL1 cofactor p47

NSFL1 cofactor p47 (NSFL1C) is a protein from Homo sapiens identified by UniProt accession Q9UNZ2, 370 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	NSFL1 cofactor p47
UniProt accession	Q9UNZ2
Gene	NSFL1C
Organism	Homo sapiens
Length	370 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

body mass index · score 0.33
neurodegenerative disease · score 0.33
myeloperoxidase measurement · score 0.06
blood protein measurement · score 0.06
reticulocyte count · score 0.02
platelet count · score 0.02
carotid artery intima media thickness · score 0.02
Immature Reticulocyte Fraction Measurement · score 0.02
azoospermia · score 0.02
platelet crit · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UNZ2-F1	alphafold	PREDICTED	74.08	—

Amino-acid sequence (370 residues)

MAAERQEALR EFVAVTGAEE DRARFFLESA GWDLQIALAS FYEDGGDEDI VTISQATPSS VSRGTAPSDN RVTSFRDLIH DQDEDEEEEE GQRFYAGGSE RSGQQIVGPP RKKSPNELVD DLFKGAKEHG AVAVERVTKS PGETSKPRPF AGGGYRLGAA PEEESAYVAG EKRQHSSQDV HVVLKLWKSG FSLDNGELRS YQDPSNAQFL ESIRRGEVPA ELRRLAHGGQ VNLDMEDHRD EDFVKPKGAF KAFTGEGQKL GSTAPQVLST SSPAQQAENE AKASSSILID ESEPTTNIQI RLADGGRLVQ KFNHSHRISD IRLFIVDARP AMAATSFILM TTFPNKELAD ESQTLKEANL LNAVIVQRLT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards