Probable G-protein coupled receptor 34 (GPR34)

About Probable G-protein coupled receptor 34

Probable G-protein coupled receptor 34 (GPR34) is a protein from Homo sapiens identified by UniProt accession Q9UPC5, 381 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

Target properties

Protein name	Probable G-protein coupled receptor 34
UniProt accession	Q9UPC5
Gene	GPR34
Organism	Homo sapiens
Length	381 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UPC5-F1	alphafold	PREDICTED	77.47	—

Amino-acid sequence (381 residues)

MRSHTITMTT TSVSSWPYSS HRMRFITNHS DQPPQNFSAT PNVTTCPMDE KLLSTVLTTS YSVIFIVGLV GNIIALYVFL GIHRKRNSIQ IYLLNVAIAD LLLIFCLPFR IMYHINQNKW TLGVILCKVV GTLFYMNMYI SIILLGFISL DRYIKINRSI QQRKAITTKQ SIYVCCIVWM LALGGFLTMI ILTLKKGGHN STMCFHYRDK HNAKGEAIFN FILVVMFWLI FLLIILSYIK IGKNLLRISK RRSKFPNSGK YATTARNSFI VLIIFTICFV PYHAFRFIYI SSQLNVSSCY WKEIVHKTNE IMLVLSSFNS CLDPVMYFLM SSNIRKIMCQ LLFRRFQGEP SRSESTSEFK PGYSLHDTSV AVKIQSSSKS T

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards