About Choline/ethanolamine transporter FLVCR2
Choline/ethanolamine transporter FLVCR2 (FLVCR2) is a protein
from Homo sapiens identified by UniProt accession
Q9UPI3, 526 residues long.
MolForge cross-references it against 0 known binders and
187 disease associations.
Target properties
| Protein name | Choline/ethanolamine transporter FLVCR2 |
|---|
| UniProt accession | Q9UPI3 |
|---|
| Gene | FLVCR2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 526 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (187)
Diseases linked to this target (Open Targets).
- Fowler syndrome · score 0.79
- genetic disorder · score 0.41
- Posterior column ataxia - retinitis pigmentosa · score 0.19
- posterior column ataxia-retinitis pigmentosa syndrome · score 0.19
- multiple sclerosis · score 0.14
- marginal zone B-cell lymphoma · score 0.12
- acute myeloid leukemia · score 0.07
- hypertriglyceridemia 2 · score 0.07
- hepatocellular carcinoma · score 0.06
- lymphocyte count · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UPI3-F1 | alphafold | PREDICTED | 80.61 | — |
Amino-acid sequence (526 residues)
MVNEGPNQEE SDDTPVPESA LQADPSVSVH PSVSVHPSVS INPSVSVHPS SSAHPSALAQ PSGLAHPSSS GPEDLSVIKV SRRRWAVVLV FSCYSMCNSF QWIQYGSINN IFMHFYGVSA FAIDWLSMCY MLTYIPLLLP VAWLLEKFGL RTIALTGSAL NCLGAWVKLG SLKPHLFPVT VVGQLICSVA QVFILGMPSR IASVWFGANE VSTACSVAVF GNQLGIAIGF LVPPVLVPNI EDRDELAYHI SIMFYIIGGV ATLLLILVII VFKEKPKYPP SRAQSLSYAL TSPDASYLGS IARLFKNLNF VLLVITYGLN AGAFYALSTL LNRMVIWHYP GEEVNAGRIG LTIVIAGMLG AVISGIWLDR SKTYKETTLV VYIMTLVGMV VYTFTLNLGH LWVVFITAGT MGFFMTGYLP LGFEFAVELT YPESEGISSG LLNISAQVFG IIFTISQGQI IDNYGTKPGN IFLCVFLTLG AALTAFIKAD LRRQKANKET LENKLQEEEE ESNTSKVPTA VSEDHL
Explore Choline/ethanolamine transporter FLVCR2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets