About B9 domain-containing protein 1
B9 domain-containing protein 1 (B9D1) is a protein
from Homo sapiens identified by UniProt accession
Q9UPM9, 204 residues long.
MolForge cross-references it against 0 known binders and
77 disease associations.
Target properties
| Protein name | B9 domain-containing protein 1 |
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| UniProt accession | Q9UPM9 |
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| Gene | B9D1 |
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| Organism | Homo sapiens |
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| Length | 204 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (77)
Diseases linked to this target (Open Targets).
- Joubert syndrome · score 0.66
- Meckel syndrome · score 0.62
- genetic disorder · score 0.41
- ciliopathy · score 0.37
- Joubert syndrome and related disorders · score 0.33
- diastolic blood pressure · score 0.30
- lymphocyte count · score 0.26
- neuritic plaque measurement · score 0.17
- cortical thickness · score 0.14
- white matter hyperintensity measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UPM9-F1 | alphafold | PREDICTED | 82.67 | — |
Amino-acid sequence (204 residues)
MATASPSVFL LMVNGQVESA QFPEYDDLYC KYCFVYGQDW APTAGLEEGI SQITSKSQDV RQALVWNFPI DVTFKSTNPY GWPQIVLSVY GPDVFGNDVV RGYGAVHVPF SPGRHKRTIP MFVPESTSKL QKFTSWFMGR RPEYTDPKVV AQGEGREVTR VRSQGFVTLL FNVVTKDMRK LGYDTGPSDT QGVLGPSPPQ SFPQ
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