PHD finger protein 24 (PHF24)

Homo sapiens — UniProt Q9UPV7

Gene: PHF24Homo sapiensSwissProt reviewed

About PHD finger protein 24

PHD finger protein 24 (PHF24) is a protein from Homo sapiens identified by UniProt accession Q9UPV7, 400 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.

Target properties

Protein namePHD finger protein 24
UniProt accessionQ9UPV7
GenePHF24
OrganismHomo sapiens
Length400 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (39)

Diseases linked to this target (Open Targets).

  • breast ductal adenocarcinoma · score 0.11
  • platelet count · score 0.08
  • psoriasis · score 0.07
  • eosinophil percentage of leukocytes · score 0.07
  • platelet crit · score 0.06
  • eosinophil count · score 0.05
  • myeloid white cell count · score 0.05
  • mean corpuscular volume · score 0.05
  • glioblastoma multiforme · score 0.04
  • neutrophil count · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UPV7-F1alphafoldPREDICTED73.26—

Amino-acid sequence (400 residues)

MGVLMSKRQT VEQVQKVSLA VSAFKDGLRD RPSIRRTGEL PGSRRGTVEG SVQEVQEEKE AEAGTSVVQE ESSAGRAAWE RLRDGRGVEP EEFDRTSRFT PPAFIRPTRK LDDDKPPEIC LEPREPVVND EMCDVCEVWT AESLFPCRVC TRVFHDGCLR RMGYIQGDSA AEVTEMAHTE TGWSCHYCDN INLLLTEEEM YSLTETFQRC KVIPDCSLTL EDFLRYRHQA AKRGDRDRAL SEEQEEQAAR QFAALDPEHR GHIEWPDFLS HESLLLLQQL RPQNSLLRLL TVKERERARA AFLARGSGST VSEAECRRAQ HSWFCKRFPE APSCSVSISH VGPIADSSPA SSSSKSQDKT LLPTEQESRF VDWPTFLQEN VLYILAARPN SAAIHLKPPG

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Quick facts

UniProtQ9UPV7
GenePHF24
OrganismHomo sapiens
Length400
Binders0
Diseases39
View on UniProt