About Protein turtle homolog B
Protein turtle homolog B (IGSF9B) is a protein
from Homo sapiens identified by UniProt accession
Q9UPX0, 1349 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Protein turtle homolog B |
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| UniProt accession | Q9UPX0 |
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| Gene | IGSF9B |
|---|
| Organism | Homo sapiens |
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| Length | 1349 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (68)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.49
- schizophrenia · score 0.48
- Parkinson disease · score 0.45
- cognitive function measurement · score 0.44
- mathematical ability · score 0.44
- neuroticism measurement · score 0.43
- autism spectrum disorder · score 0.40
- alcohol consumption measurement · score 0.40
- attention deficit hyperactivity disorder · score 0.39
- grip strength measurement · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UPX0-F1 | alphafold | PREDICTED | 62.24 | — |
Amino-acid sequence (1349 residues)
MIWYVATFIA SVIGTRGLAA EGAHGLREEP EFVTARAGES VVLRCDVIHP VTGQPPPYVV EWFKFGVPIP IFIKFGYYPP HVDPEYAGRA SLHDKASLRL EQVRSEDQGW YECKVLMLDQ QYDTFHNGSW VHLTINAPPT FTETPPQYIE AKEGGSITMT CTAFGNPKPI VTWLKEGTLL GASGKYQVSD GSLTVTSVSR EDRGAYTCRA YSIQGEAVHT THLLVQGPPF IVSPPENITV NISQDALLTC RAEAYPGNLT YTWYWQDENV YFQNDLKLRV RILIDGTLII FRVKPEDSGK YTCVPSNSLG RSPSASAYLT VQYPARVLNM PPVIYVPVGI HGYIRCPVDA EPPATVVKWN KDGRPLQVEK NLGWTLMEDG SIRIEEATEE ALGTYTCVPY NTLGTMGQSA PARLVLKDPP YFTVLPGWEY RQEAGRELLI PCAAAGDPFP VITWRKVGKP SRSKHSALPS GSLQFRALSK EDHGEWECVA TNVVTSITAS THLTVIGTSP HAPGSVRVQV SMTTANVSWE PGYDGGYEQT FSVWMKRAQF GPHDWLSLPV PPGPSWLLVD TLEPETAYQF SVLAQNKLGT SAFSEVVTVN TLAFPITTPE PLVLVTPPRC LIANRTQQGV LLSWLPPANH SFPIDRYIME FRVAERWELL DDGIPGTEGE FFAKDLSQDT WYEFRVLAVM QDLISEPSNI AGVSSTDIFP QPDLTEDGLA RPVLAGIVAT ICFLAAAILF STLAACFVNK QRKRKLKRKK DPPLSITHCR KSLESPLSSG KVSPESIRTL RAPSESSDDQ GQPAAKRMLS PTREKELSLY KKTKRAISSK KYSVAKAEAE AEATTPIELI SRGPDGRFVM DPAEMEPSLK SRRIEGFPFA EETDMYPEFR QSDEENEDPL VPTSVAALKS QLTPLSSSQE SYLPPPAYSP RFQPRGLEGP GGLEGRLQAT GQARPPAPRP FHHGQYYGYL SSSSPGEVEP PPFYVPEVGS PLSSVMSSPP LPTEGPFGHP TIPEENGENA SNSTLPLTQT PTGGRSPEPW GRPEFPFGGL ETPAMMFPHQ LPPCDVPESL QPKAGLPRGL PPTSLQVPAA YPGILSLEAP KGWAGKSPGR GPVPAPPAAK WQDRPMQPLV SQGQLRHTSQ GMGIPVLPYP EPAEPGAHGG PSTFGLDTRW YEPQPRPRPS PRQARRAEPS LHQVVLQPSR LSPLTQSPLS SRTGSPELAA RARPRPGLLQ QAEMSEITLQ PPAAVSFSRK STPSTGSPSQ SSRSGSPSYR PAMGFTTLAT GYPSPPPGPA PAGPGDSLDV FGQTPSPRRT GEELLRPETP PPTLPTSGKL QRDRPAPATS PPERALSKL
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