RING finger protein 24 (RNF24)

Homo sapiens — UniProt Q9Y225

Gene: RNF24Homo sapiensSwissProt reviewed

About RING finger protein 24

RING finger protein 24 (RNF24) is a protein from Homo sapiens identified by UniProt accession Q9Y225, 148 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.

Target properties

Protein nameRING finger protein 24
UniProt accessionQ9Y225
GeneRNF24
OrganismHomo sapiens
Length148 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (79)

Diseases linked to this target (Open Targets).

  • electrocardiography · score 0.23
  • PR interval · score 0.22
  • aspartate aminotransferase measurement · score 0.21
  • vital capacity · score 0.15
  • monocyte percentage of leukocytes · score 0.10
  • Blackfan-Diamond anemia · score 0.09
  • hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.07
  • alpha thalassemia-intellectual disability syndrome type 1 · score 0.06
  • Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.06
  • alpha-thalassemia-myelodysplastic syndrome · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y225-F1alphafoldPREDICTED70.63—

Amino-acid sequence (148 residues)

MSSDFPHYNF RMPNIGFQNL PLNIYIVVFG TAIFVFILSL LFCCYLIRLR HQAHKEFYAY KQVILKEKVK ELNLHELCAV CLEDFKPRDE LGICPCKHAF HRKCLIKWLE VRKVCPLCNM PVLQLAQLHS KQDRGPPQGP LPGAENIV

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Quick facts

UniProtQ9Y225
GeneRNF24
OrganismHomo sapiens
Length148
Binders0
Diseases79
View on UniProt