About RING finger protein 24
RING finger protein 24 (RNF24) is a protein
from Homo sapiens identified by UniProt accession
Q9Y225, 148 residues long.
MolForge cross-references it against 0 known binders and
79 disease associations.
Target properties
| Protein name | RING finger protein 24 |
| UniProt accession | Q9Y225 |
| Gene | RNF24 |
| Organism | Homo sapiens |
| Length | 148 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (79)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.23
- PR interval · score 0.22
- aspartate aminotransferase measurement · score 0.21
- vital capacity · score 0.15
- monocyte percentage of leukocytes · score 0.10
- Blackfan-Diamond anemia · score 0.09
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.07
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.06
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.06
- alpha-thalassemia-myelodysplastic syndrome · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9Y225-F1 | alphafold | PREDICTED | 70.63 | — |
Amino-acid sequence (148 residues)
MSSDFPHYNF RMPNIGFQNL PLNIYIVVFG TAIFVFILSL LFCCYLIRLR HQAHKEFYAY KQVILKEKVK ELNLHELCAV CLEDFKPRDE LGICPCKHAF HRKCLIKWLE VRKVCPLCNM PVLQLAQLHS KQDRGPPQGP LPGAENIV
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