About Chromodomain Y-like protein
Chromodomain Y-like protein (CDYL) is a protein
from Homo sapiens identified by UniProt accession
Q9Y232, 598 residues long.
MolForge cross-references it against 0 known binders and
58 disease associations.
Target properties
| Protein name | Chromodomain Y-like protein |
|---|
| UniProt accession | Q9Y232 |
|---|
| Gene | CDYL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 598 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (58)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.43
- Red cell distribution width · score 0.40
- Parkinson disease · score 0.37
- multiple sclerosis · score 0.37
- Alzheimer disease · score 0.37
- lysosomal storage disease · score 0.37
- gut microbiome measurement · score 0.30
- PHF-tau measurement · score 0.28
- HbA1c measurement · score 0.28
- mean corpuscular hemoglobin concentration · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y232-F1 | alphafold | PREDICTED | 67.85 | — |
Amino-acid sequence (598 residues)
MTFQASHRSA WGKSRKKNWQ YEGPTQKLFL KRNNVSAPDG PSDPSISVSS EQSGAQQPPA LQVERIVDKR KNKKGKTEYL VRWKGYDSED DTWEPEQHLV NCEEYIHDFN RRHTEKQKES TLTRTNRTSP NNARKQISRS TNSNFSKTSP KALVIGKDHE SKNSQLFAAS QKFRKNTAPS LSSRKNMDLA KSGIKILVPK SPVKSRTAVD GFQSESPEKL DPVEQGQEDT VAPEVAAEKP VGALLGPGAE RARMGSRPRI HPLVPQVPGP VTAAMATGLA VNGKGTSPFM DALTANGTTN IQTSVTGVTA SKRKFIDDRR DQPFDKRLRF SVRQTESAYR YRDIVVRKQD GFTHILLSTK SSENNSLNPE VMREVQSALS TAAADDSKLV LLSAVGSVFC CGLDFIYFIR RLTDDRKRES TKMAEAIRNF VNTFIQFKKP IIVAVNGPAI GLGASILPLC DVVWANEKAW FQTPYTTFGQ SPDGCSTVMF PKIMGGASAN EMLLSGRKLT AQEACGKGLV SQVFWPGTFT QEVMVRIKEL ASCNPVVLEE SKALVRCNMK MELEQANERE CEVLKKIWGS AQGMDSMLKY LQRKIDEF
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