HIG1 domain family member 1A, mitochondrial (HIGD1A)

About HIG1 domain family member 1A, mitochondrial

HIG1 domain family member 1A, mitochondrial (HIGD1A) is a protein from Homo sapiens identified by UniProt accession Q9Y241, 93 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

Target properties

Protein name	HIG1 domain family member 1A, mitochondrial
UniProt accession	Q9Y241
Gene	HIGD1A
Organism	Homo sapiens
Length	93 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (48)

Diseases linked to this target (Open Targets).

monocyte count · score 0.13
body fat distribution · score 0.10
hepatocellular carcinoma · score 0.07
neoplasm · score 0.06
eosinophil count · score 0.05
protein measurement · score 0.03
fetal genotype effect measurement · score 0.03
glioblastoma · score 0.02
colorectal adenocarcinoma · score 0.02
monokine induced by gamma interferon measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y241-F1	alphafold	PREDICTED	64.04	—

Amino-acid sequence (93 residues)

MSTDTGVSLP SYEEDQGSKL IRKAKEAPFV PVGIAGFAAI VAYGLYKLKS RGNTKMSIHL IHMRVAAQGF VVGAMTVGMG YSMYREFWAK PKP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards