About Protein FAM50B
Protein FAM50B (FAM50B) is a protein
from Homo sapiens identified by UniProt accession
Q9Y247, 325 residues long.
MolForge cross-references it against 0 known binders and
35 disease associations.
Target properties
| Protein name | Protein FAM50B |
|---|
| UniProt accession | Q9Y247 |
|---|
| Gene | FAM50B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 325 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (35)
Diseases linked to this target (Open Targets).
- adolescent idiopathic scoliosis · score 0.26
- protein measurement · score 0.22
- metabolite measurement · score 0.21
- neuroticism measurement · score 0.10
- neurofibrillary tangles measurement · score 0.10
- clavicle fracture · score 0.06
- Barrett's esophagus · score 0.03
- Esophagitis · score 0.03
- optic cup area measurement · score 0.02
- embryonal carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y247-F1 | alphafold | PREDICTED | 76.69 | — |
Amino-acid sequence (325 residues)
MAQYKGTMRE AGRAMHLLKK RERQREQMEV LKQRIAEETI LKSQVDKRFS AHYDAVEAEL KSSTVGLVTL NDMKARQEAL VRERERQLAK RQHLEEQRLQ QERQREQEQR RERKRKISCL SFALDDLDDQ ADAAEARRAG NLGKNPDVDT SFLPDRDREE EENRLREELR QEWEAQREKV KDEEMEVTFS YWDGSGHRRT VRVRKGNTVQ QFLKKALQGL RKDFLELRSA GVEQLMFIKE DLILPHYHTF YDFIIARARG KSGPLFSFDV HDDVRLLSDA TMEKDESHAG KVVLRSWYEK NKHIFPASRW EAYDPEKKWD KYTIR
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