PRELI domain-containing protein 1, mitochondrial…

About PRELI domain-containing protein 1, mitochondrial

PRELI domain-containing protein 1, mitochondrial (PRELID1) is a protein from Homo sapiens identified by UniProt accession Q9Y255, 219 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.

Target properties

Protein name	PRELI domain-containing protein 1, mitochondrial
UniProt accession	Q9Y255
Gene	PRELID1
Organism	Homo sapiens
Length	219 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (64)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.54
squamous cell lung carcinoma · score 0.23
head and neck squamous cell carcinoma · score 0.23
endometrial cancer · score 0.23
diastolic blood pressure · score 0.19
uric acid measurement · score 0.15
lean body mass · score 0.15
blood protein measurement · score 0.15
prostate adenocarcinoma · score 0.15
mathematical ability · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y255-F1	alphafold	PREDICTED	90.53	—

Amino-acid sequence (219 residues)

MVKYFLGQSV LRSSWDQVFA AFWQRYPNPY SKHVLTEDIV HREVTPDQKL LSRRLLTKTN RMPRWAERLF PANVAHSVYV LEDSIVDPQN QTMTTFTWNI NHARLMVVEE RCVYCVNSDN SGWTEIRREA WVSSSLFGVS RAVQEFGLAR FKSNVTKTMK GFEYILAKLQ GEAPSKTLVE TAKEAKEKAK ETALAATEKA KDLASKAATK KQQQQQQFV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

PRELI domain-containing protein 1, mitochondrial (PRELID1)