About Angiopoietin-4
Angiopoietin-4 (ANGPT4) is a protein
from Homo sapiens identified by UniProt accession
Q9Y264, 503 residues long.
MolForge cross-references it against 0 known binders and
65 disease associations.
Target properties
| Protein name | Angiopoietin-4 |
|---|
| UniProt accession | Q9Y264 |
|---|
| Gene | ANGPT4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 503 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (65)
Diseases linked to this target (Open Targets).
- food allergy measurement · score 0.28
- glioblastoma multiforme · score 0.24
- breast adenocarcinoma · score 0.23
- head and neck squamous cell carcinoma · score 0.21
- cutaneous melanoma · score 0.18
- lung adenocarcinoma · score 0.18
- endometrial cancer · score 0.18
- low grade glioma · score 0.14
- HIV-1 infection · score 0.13
- peripheral neuropathy · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y264-F1 | alphafold | PREDICTED | 82.81 | — |
Amino-acid sequence (503 residues)
MLSQLAMLQG SLLLVVATMS VAQQTRQEAD RGCETLVVQH GHCSYTFLLP KSEPCPPGPE VSRDSNTLQR ESLANPLHLG KLPTQQVKQL EQALQNNTQW LKKLERAIKT ILRSKLEQVQ QQMAQNQTAP MLELGTSLLN QTTAQIRKLT DMEAQLLNQT SRMDAQMPET FLSTNKLENQ LLLQRQKLQQ LQGQNSALEK RLQALETKQQ EELASILSKK AKLLNTLSRQ SAALTNIERG LRGVRHNSSL LQDQQHSLRQ LLVLLRHLVQ ERANASAPAF IMAGEQVFQD CAEIQRSGAS ASGVYTIQVS NATKPRKVFC DLQSSGGRWT LIQRRENGTV NFQRNWKDYK QGFGDPAGEH WLGNEVVHQL TRRAAYSLRV ELQDWEGHEA YAQYEHFHLG SENQLYRLSV VGYSGSAGRQ SSLVLQNTSF STLDSDNDHC LCKCAQVMSG GWWFDACGLS NLNGVYYHAP DNKYKMDGIR WHYFKGPSYS LRASRMMIRP LDI
Explore Angiopoietin-4 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets