Nuclear migration protein nudC (NUDC)

About Nuclear migration protein nudC

Nuclear migration protein nudC (NUDC) is a protein from Homo sapiens identified by UniProt accession Q9Y266, 331 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.

Target properties

Protein name	Nuclear migration protein nudC
UniProt accession	Q9Y266
Gene	NUDC
Organism	Homo sapiens
Length	331 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (74)

Diseases linked to this target (Open Targets).

obesity · score 0.43
inherited obesity · score 0.32
platelet count · score 0.20
systolic blood pressure · score 0.19
age-related macular degeneration · score 0.17
vitamin D measurement · score 0.15
IGF-1 measurement · score 0.15
platelet crit · score 0.12
high density lipoprotein cholesterol measurement · score 0.12
neutrophil count · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y266-F1	alphafold	PREDICTED	81.37	—

Amino-acid sequence (331 residues)

MGGEQEEERF DGMLLAMAQQ HEGGVQELVN TFFSFLRRKT DFFIGGEEGM AEKLITQTFS HHNQLAQKTR REKRARQEAE RREKAERAAR LAKEAKSETS GPQIKELTDE EAERLQLEID QKKDAENHEA QLKNGSLDSP GKQDTEEDEE EDEKDKGKLK PNLGNGADLP NYRWTQTLSE LDLAVPFCVN FRLKGKDMVV DIQRRHLRVG LKGQPAIIDG ELYNEVKVEE SSWLIEDGKV VTVHLEKINK MEWWSRLVSS DPEINTKKIN PENSKLSDLD SETRSMVEKM MYDQRQKSMG LPTSDEQKKQ EILKKFMDQH PEMDFSKAKF N

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards