Dexamethasone-induced Ras-related protein 1 (RASD1)

About Dexamethasone-induced Ras-related protein 1

Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein from Homo sapiens identified by UniProt accession Q9Y272, 281 residues long. MolForge cross-references it against 0 known binders and 147 disease associations.

Target properties

Protein name	Dexamethasone-induced Ras-related protein 1
UniProt accession	Q9Y272
Gene	RASD1
Organism	Homo sapiens
Length	281 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (147)

Diseases linked to this target (Open Targets).

chronotype measurement · score 0.43
circadian rhythm · score 0.27
lean body mass · score 0.27
glucose measurement · score 0.26
diabetes mellitus · score 0.26
triglyceride measurement · score 0.25
body weight · score 0.21
protein measurement · score 0.15
BMI-adjusted waist-hip ratio · score 0.14
base metabolic rate measurement · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y272-F1	alphafold	PREDICTED	79.86	—

Amino-acid sequence (281 residues)

MKLAAMIKKM CPSDSELSIP AKNCYRMVIL GSSKVGKTAI VSRFLTGRFE DAYTPTIEDF HRKFYSIRGE VYQLDILDTS GNHPFPAMRR LSILTGDVFI LVFSLDNRDS FEEVQRLRQQ ILDTKSCLKN KTKENVDVPL VICGNKGDRD FYREVDQREI EQLVGDDPQR CAYFEISAKK NSSLDQMFRA LFAMAKLPSE MSPDLHRKVS VQYCDVLHKK ALRNKKLLRA GSGGGGGDPG DAFGIVAPFA RRPSVHSDLM YIREKASAGS QAKDKERCVI S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards