About Sodium-dependent multivitamin transporter
Sodium-dependent multivitamin transporter (SLC5A6) is a protein
from Homo sapiens identified by UniProt accession
Q9Y289, 635 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | Sodium-dependent multivitamin transporter |
|---|
| UniProt accession | Q9Y289 |
|---|
| Gene | SLC5A6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 635 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- neurodegeneration, infantile-onset, biotin-responsive · score 0.74
- peripheral motor neuropathy, childhood-onset, biotin-responsive · score 0.60
- genetic disorder · score 0.19
- Neurodevelopmental disorder · score 0.18
- blood metabolite measurement · score 0.13
- cutaneous melanoma · score 0.12
- serum metabolite measurement · score 0.11
- Crigler-Najjar syndrome type 2 · score 0.06
- schizophrenia · score 0.06
- maple syrup urine disease · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y289-F1 | alphafold | PREDICTED | 79.40 | — |
Amino-acid sequence (635 residues)
MSVGVSTSAP LSPTSGTSVG MSTFSIMDYV VFVLLLVLSL AIGLYHACRG WGRHTVGELL MADRKMGCLP VALSLLATFQ SAVAILGVPS EIYRFGTQYW FLGCCYFLGL LIPAHIFIPV FYRLHLTSAY EYLELRFNKT VRVCGTVTFI FQMVIYMGVV LYAPSLALNA VTGFDLWLSV LALGIVCTVY TALGGLKAVI WTDVFQTLVM FLGQLAVIIV GSAKVGGLGR VWAVASQHGR ISGFELDPDP FVRHTFWTLA FGGVFMMLSL YGVNQAQVQR YLSSRTEKAA VLSCYAVFPF QQVSLCVGCL IGLVMFAYYQ EYPMSIQQAQ AAPDQFVLYF VMDLLKGLPG LPGLFIACLF SGSLSTISSA FNSLATVTME DLIRPWFPEF SEARAIMLSR GLAFGYGLLC LGMAYISSQM GPVLQAAISI FGMVGGPLLG LFCLGMFFPC ANPPGAVVGL LAGLVMAFWI GIGSIVTSMG SSMPPSPSNG SSFSLPTNLT VATVTTLMPL TTFSKPTGLQ RFYSLSYLWY SAHNSTTVIV VGLIVSLLTG RMRGRSLNPA TIYPVLPKLL SLLPLSCQKR LHCRSYGQDH LDTGLFPEKP RNGVLGDSRD KEAMALDGTA YQGSSSTCIL QETSL
Explore Sodium-dependent multivitamin transporter with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets