About Beta-1,3-galactosyltransferase 5
Beta-1,3-galactosyltransferase 5 (B3GALT5) is a protein
from Homo sapiens identified by UniProt accession
Q9Y2C3, 310 residues long.
MolForge cross-references it against 0 known binders and
49 disease associations.
Target properties
| Protein name | Beta-1,3-galactosyltransferase 5 |
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| UniProt accession | Q9Y2C3 |
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| Gene | B3GALT5 |
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| Organism | Homo sapiens |
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| Length | 310 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (49)
Diseases linked to this target (Open Targets).
- asthma · score 0.12
- hepatocellular carcinoma · score 0.10
- neoplasm · score 0.08
- metabolite measurement · score 0.08
- Obesity · score 0.07
- Insulin resistance · score 0.04
- colorectal cancer · score 0.04
- metabolic disease · score 0.04
- COVID-19 · score 0.03
- lung adenocarcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y2C3-F1 | alphafold | PREDICTED | 92.74 | — |
Amino-acid sequence (310 residues)
MAFPKMRLMY ICLLVLGALC LYFSMYSLNP FKEQSFVYKK DGNFLKLPDT DCRQTPPFLV LLVTSSHKQL AERMAIRQTW GKERMVKGKQ LKTFFLLGTT SSAAETKEVD QESQRHGDII QKDFLDVYYN LTLKTMMGIE WVHRFCPQAA FVMKTDSDMF INVDYLTELL LKKNRTTRFF TGFLKLNEFP IRQPFSKWFV SKSEYPWDRY PPFCSGTGYV FSGDVASQVY NVSKSVPYIK LEDVFVGLCL ERLNIRLEEL HSQPTFFPGG LRFSVCLFRR IVACHFIKPR TLLDYWQALE NSRGEDCPPV
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