UDP-N-acetylglucosamine transporter (SLC35A3)

About UDP-N-acetylglucosamine transporter

UDP-N-acetylglucosamine transporter (SLC35A3) is a protein from Homo sapiens identified by UniProt accession Q9Y2D2, 325 residues long. MolForge cross-references it against 0 known binders and 152 disease associations.

Target properties

Protein name	UDP-N-acetylglucosamine transporter
UniProt accession	Q9Y2D2
Gene	SLC35A3
Organism	Homo sapiens
Length	325 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (152)

Diseases linked to this target (Open Targets).

autism spectrum disorder - epilepsy - arthrogryposis syndrome · score 0.66
Autism spectrum disorder-epilepsy-arthrogryposis syndrome · score 0.46
epilepsy syndrome · score 0.37
distal arthrogryposis · score 0.37
developmental disorder of mental health · score 0.37
genetic disorder · score 0.33
neurodegenerative disease · score 0.28
gut microbiome measurement · score 0.23
arthrogryposis multiplex congenita · score 0.17
autosomal recessive spondylocostal dysostosis · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y2D2-F1	alphafold	PREDICTED	89.32	—

Amino-acid sequence (325 residues)

MFANLKYVSL GILVFQTTSL VLTMRYSRTL KEEGPRYLSS TAVVVAELLK IMACILLVYK DSKCSLRALN RVLHDEILNK PMETLKLAIP SGIYTLQNNL LYVALSNLDA ATYQVTYQLK ILTTALFSVS MLSKKLGVYQ WLSLVILMTG VAFVQWPSDS QLDSKELSAG SQFVGLMAVL TACFSSGFAG VYFEKILKET KQSVWIRNIQ LGFFGSIFGL MGVYIYDGEL VSKNGFFQGY NRLTWIVVVL QALGGLVIAA VIKYADNILK GFATSLSIIL STLISYFWLQ DFVPTSVFFL GAILVITATF LYGYDPKPAG NPTKA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards