About Protein SSUH2 homolog
Protein SSUH2 homolog (SSUH2) is a protein
from Homo sapiens identified by UniProt accession
Q9Y2M2, 375 residues long.
MolForge cross-references it against 0 known binders and
192 disease associations.
Target properties
| Protein name | Protein SSUH2 homolog |
|---|
| UniProt accession | Q9Y2M2 |
|---|
| Gene | SSUH2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 375 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (192)
Diseases linked to this target (Open Targets).
- Prolonged QT interval · score 0.54
- rippling muscle disease 2 · score 0.51
- limb-girdle muscular dystrophy · score 0.51
- Elevated circulating creatine kinase concentration · score 0.50
- isolated asymptomatic elevation of creatine phosphokinase · score 0.50
- distal myopathy · score 0.49
- long QT syndrome 9 · score 0.48
- hypertrophic cardiomyopathy 1 · score 0.44
- Rare familial disorder with hypertrophic cardiomyopathy · score 0.44
- dentin dysplasia type I · score 0.39
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y2M2-F1 | alphafold | PREDICTED | 80.78 | — |
Amino-acid sequence (375 residues)
MDRDLNEDDS VVDLSFEAES PLAPPTELLE RLPSYDWLLQ GGRGQIFFPP LEAPGRPQEQ RSWPSFLEHR VPAMTEEVAR EALLSFVDSK CCYSSTVAGD LVIQELKRQT LCRYRLETFS ESRISEWTFQ PFTNHSVDGP QRGASPRLWD IKVQGPPMFQ EDTRKFQVPH SSLVKECHKC HGRGRYKCSG CHGAGTVRCP SCCGAKRKAK QSRRCQLCAG SGRRRCSTCS GRGNKTCATC KGEKKLLHFI QLVIMWKNSL FEFVSEHRLN CPRELLAKAK GENLFKDENS VVYPIVDFPL RDISLASQRG IAEHSAALAS RARVLQQRQT IELIPLTEVH YWYQGKTYVY YIYGTDHQVY AVDYPERYCC GCTIV
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