About Long-chain fatty acid transport protein 6
Long-chain fatty acid transport protein 6 (SLC27A6) is a protein
from Homo sapiens identified by UniProt accession
Q9Y2P4, 619 residues long.
MolForge cross-references it against 0 known binders and
87 disease associations.
Target properties
| Protein name | Long-chain fatty acid transport protein 6 |
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| UniProt accession | Q9Y2P4 |
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| Gene | SLC27A6 |
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| Organism | Homo sapiens |
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| Length | 619 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (87)
Diseases linked to this target (Open Targets).
- refractive error measurement · score 0.44
- heel bone mineral density · score 0.41
- cortical thickness · score 0.38
- systolic blood pressure · score 0.30
- hypertension · score 0.29
- Agents acting on the renin-angiotensin system use measurement · score 0.27
- bone density · score 0.26
- diastolic blood pressure · score 0.26
- atrial fibrillation · score 0.25
- diffuse plaque measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y2P4-F1 | alphafold | PREDICTED | 90.89 | — |
Amino-acid sequence (619 residues)
MLLSWLTVLG AGMVVLHFLQ KLLFPYFWDD FWFVLKVVLI IIRLKKYEKR GELVTVLDKF LSHAKRQPRK PFIIYEGDIY TYQDVDKRSS RVAHVFLNHS SLKKGDTVAL LMSNEPDFVH VWFGLAKLGC VVAFLNTNIR SNSLLNCIRA CGPRALVVGA DLLGTVEEIL PSLSENISVW GMKDSVPQGV ISLKEKLSTS PDEPVPRSHH VVSLLKSTCL YIFTSGTTGL PKAAVISQLQ VLRGSAVLWA FGCTAHDIVY ITLPLYHSSA AILGISGCVE LGATCVLKKK FSASQFWSDC KKYDVTVFQY IGELCRYLCK QSKREGEKDH KVRLAIGNGI RSDVWREFLD RFGNIKVCEL YAATESSISF MNYTGRIGAI GRTNLFYKLL STFDLIKYDF QKDEPMRNEQ GWCIHVKKGE PGLLISRVNA KNPFFGYAGP YKHTKDKLLC DVFKKGDVYL NTGDLIVQDQ DNFLYFWDRT GDTFRWKGEN VATTEVADVI GMLDFIQEAN VYGVAISGYE GRAGMASIIL KPNTSLDLEK VYEQVVTFLP AYACPRFLRI QEKMEATGTF KLLKHQLVED GFNPLKISEP LYFMDNLKKS YVLLTRELYD QIMLGEIKL
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