Potassium channel subfamily K member 7 (KCNK7)

About Potassium channel subfamily K member 7

Potassium channel subfamily K member 7 (KCNK7) is a protein from Homo sapiens identified by UniProt accession Q9Y2U2, 307 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

Target properties

Protein name	Potassium channel subfamily K member 7
UniProt accession	Q9Y2U2
Gene	KCNK7
Organism	Homo sapiens
Length	307 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (48)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.22
aspartate aminotransferase measurement · score 0.17
cutaneous melanoma · score 0.16
calcium measurement · score 0.14
glucose measurement · score 0.11
total cholesterol measurement · score 0.10
serum albumin measurement · score 0.09
sex hormone-binding globulin measurement · score 0.09
mean corpuscular hemoglobin · score 0.08
Red cell distribution width · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y2U2-F1	alphafold	PREDICTED	82.43	—

Amino-acid sequence (307 residues)

MGGLRPWSRY GLLVVAHLLA LGLGAVVFQA LEGPPACRLQ AELRAELAAF QAEHRACLPP GALEELLGTA LATQAHGVST LGNSSEGRTW DLPSALLFAA SILTTTGYGH MAPLSPGGKA FCMVYAALGL PASLALVATL RHCLLPVLSR PRAWVAVHWQ LSPARAALLQ AVALGLLVAS SFVLLPALVL WGLQGDCSLL GAVYFCFSSL STIGLEDLLP GRGRSLHPVI YHLGQLALLG YLLLGLLAML LAVETFSELP QVRAMGKFFR PSGPVTAEDQ GGILGQDELA LSTLPPAAPA SGQAPAC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards