About rRNA-processing protein FCF1 homolog
rRNA-processing protein FCF1 homolog (FCF1) is a protein
from Homo sapiens identified by UniProt accession
Q9Y324, 198 residues long.
MolForge cross-references it against 0 known binders and
40 disease associations.
Target properties
| Protein name | rRNA-processing protein FCF1 homolog |
|---|
| UniProt accession | Q9Y324 |
|---|
| Gene | FCF1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 198 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (40)
Diseases linked to this target (Open Targets).
- Parkinson disease · score 0.47
- Alzheimer disease · score 0.46
- lysosomal storage disease · score 0.46
- neurodegenerative disease · score 0.46
- multiple sclerosis · score 0.46
- endometrial cancer · score 0.10
- major depressive disorder · score 0.06
- unipolar depression · score 0.06
- grip strength measurement · score 0.05
- FEV/FVC ratio · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y324-F1 | alphafold | PREDICTED | 83.73 | — |
Amino-acid sequence (198 residues)
MGKQKKTRKY ATMKRMLSLR DQRLKEKDRL KPKKKEKKDP SALKEREVPQ HPSCLFFQYN TQLGPPYHIL VDTNFINFSI KAKLDLVQSM MDCLYAKCIP CITDCVMAEI EKLGQKYRVA LRIAKDPRFE RLPCTHKGTY ADDCLVQRVT QHKCYIVATV DRDLKRRIRK IPGVPIMYIS NHRYNIERMP DDYGAPRF
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