Neuronal vesicle trafficking-associated protein 2…

About Neuronal vesicle trafficking-associated protein 2

Neuronal vesicle trafficking-associated protein 2 (NSG2) is a protein from Homo sapiens identified by UniProt accession Q9Y328, 171 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.

Target properties

Protein name	Neuronal vesicle trafficking-associated protein 2
UniProt accession	Q9Y328
Gene	NSG2
Organism	Homo sapiens
Length	171 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (85)

Diseases linked to this target (Open Targets).

chronotype measurement · score 0.33
musculoskeletal system disease · score 0.33
connective tissue disease · score 0.33
protein measurement · score 0.21
hair color · score 0.18
delirium · score 0.18
PHF-tau measurement · score 0.14
balding measurement · score 0.14
hair colour measurement · score 0.13
Inguinal hernia · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y328-F1	alphafold	PREDICTED	58.85	—

Amino-acid sequence (171 residues)

MVKLNSNPSE KGTKPPSVED GFQTVPLITP LEVNHLQLPA PEKVIVKTRT EYQPEQKNKG KFRVPKIAEF TVTILVSLAL AFLACIVFLV VYKAFTYDHS CPEGFVYKHK RCIPASLDAY YSSQDPNSRS RFYTVISHYS VAKQSTARAI GPWLSAAAVI HEPKPPKTQG H

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Neuronal vesicle trafficking-associated protein 2 (NSG2)