About von Willebrand factor A domain-containing protein 7
von Willebrand factor A domain-containing protein 7 (VWA7) is a protein
from Homo sapiens identified by UniProt accession
Q9Y334, 891 residues long.
MolForge cross-references it against 0 known binders and
72 disease associations.
Target properties
| Protein name | von Willebrand factor A domain-containing protein 7 |
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| UniProt accession | Q9Y334 |
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| Gene | VWA7 |
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| Organism | Homo sapiens |
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| Length | 891 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (72)
Diseases linked to this target (Open Targets).
- celiac disease · score 0.34
- malabsorption syndrome · score 0.34
- fat body mass · score 0.25
- lymphocyte count · score 0.24
- monocyte count · score 0.23
- body fat percentage · score 0.21
- psoriasis · score 0.18
- body weights and measures · score 0.17
- leukocyte count · score 0.17
- body weight · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y334-F1 | alphafold | PREDICTED | 83.57 | — |
Amino-acid sequence (891 residues)
MLPTEVPQSH PGPSALLLLQ LLLPPTSAFF PNIWSLLAAP GSITHQDLTE EAALNVTLQL FLEQPPPGRP PLRLEDFLGR TLLADDLFAA YFGPGSSRRF RAALGEVSRA NAAQDFLPTS RNDPDLHFDA ERLGQGRARL VGALRETVVA ARALDHTLAR QRLGAALHAL QDFYSHSNWV ELGEQQPHPH LLWPRQELQN LAQVADPTCS DCEELSCPRN WLGFTLLTSG YFGTHPPKPP GKCSHGGHFD RSSSQPPRGG INKDSTSPGF SPHHMLHLQA AKLALLASIQ AFSLLRSRLG DRDFSRLLDI TPASSLSFVL DTTGSMGEEI NAAKIQARHL VEQRRGSPME PVHYVLVPFH DPGFGPVFTT SDPDSFWQQL NEIHALGGGD EPEMCLSALQ LALLHTPPLS DIFVFTDASP KDAFLTNQVE SLTQERRCRV TFLVTEDTSR VQGRARREIL SPLRFEPYKA VALASGGEVI FTKDQHIRDV AAIVGESMAA LVTLPLDPPV VVPGQPLVFS VDGLLQKITV RIHGDISSFW IKNPAGVSQG QEEGGGPLGH TRRFGQFWMV TMDDPPQTGT WEIQVTAEDT PGVRVQAQTS LDFLFHFGIP MEDGPHPGLY PLTQPVAGLQ TQLLVEVTGL GSRANPGDPQ PHFSHVILRG VPEGAELGQV PLEPVGPPER GLLAASLSPT LLSTPRPFSL ELIGQDAAGR RLHRAAPQPS TVVPVLLELS GPSGFLAPGS KVPLSLRIAS FSGPQDLDLR TFVNPSFSLT SNLSRAHLEL NESAWGRLWL EVPDSAAPDS VVMVTVTAGG REANPVPPTH AFLRLLVSAP APQDRHTTPT GSSDPILTTA TPAFSPFTLV TQGRAGAGLA AGSPWWGTVG GVLLLLGLAS W
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