Sorting nexin-24 (SNX24)

About Sorting nexin-24

Sorting nexin-24 (SNX24) is a protein from Homo sapiens identified by UniProt accession Q9Y343, 169 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

Target properties

Protein name	Sorting nexin-24
UniProt accession	Q9Y343
Gene	SNX24
Organism	Homo sapiens
Length	169 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

mean platelet volume · score 0.36
neutrophil count · score 0.30
high density lipoprotein cholesterol measurement · score 0.21
diverticulitis · score 0.21
bowel opening frequency · score 0.18
platelet crit · score 0.18
vital capacity · score 0.17
leukocyte count · score 0.17
aortic measurement · score 0.15
apolipoprotein A 1 measurement · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y343-F1	alphafold	PREDICTED	79.79	—

Amino-acid sequence (169 residues)

MEVYIPSFRY EESDLERGYT VFKIEVLMNG RKHFVEKRYS EFHALHKKLK KCIKTPEIPS KHVRNWVPKV LEQRRQGLET YLQAVILENE ELPKLFLDFL NVRHLPSLPK AESCGSFDET ESEESSKLSH QPVLLFLRDP YVLPAASDFP NVVIEGVLHG IFYPHLQPR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards