About Calcium-binding protein 39
Calcium-binding protein 39 (CAB39) is a protein
from Homo sapiens identified by UniProt accession
Q9Y376, 341 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | Calcium-binding protein 39 |
|---|
| UniProt accession | Q9Y376 |
|---|
| Gene | CAB39 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 341 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (55)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- lymphocyte count · score 0.31
- lung adenocarcinoma · score 0.26
- lymphocyte percentage of leukocytes · score 0.24
- neutrophil percentage of leukocytes · score 0.22
- endometrial cancer · score 0.18
- multiple myeloma · score 0.16
- gastric carcinoma · score 0.15
- hepatocellular carcinoma · score 0.07
- gut microbiome measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y376-F1 | alphafold | PREDICTED | 94.69 | — |
Amino-acid sequence (341 residues)
MPFPFGKSHK SPADIVKNLK ESMAVLEKQD ISDKKAEKAT EEVSKNLVAM KEILYGTNEK EPQTEAVAQL AQELYNSGLL STLVADLQLI DFEGKKDVAQ IFNNILRRQI GTRTPTVEYI CTQQNILFML LKGYESPEIA LNCGIMLREC IRHEPLAKII LWSEQFYDFF RYVEMSTFDI ASDAFATFKD LLTRHKLLSA EFLEQHYDRF FSEYEKLLHS ENYVTKRQSL KLLGELLLDR HNFTIMTKYI SKPENLKLMM NLLRDKSRNI QFEAFHVFKV FVANPNKTQP ILDILLKNQA KLIEFLSKFQ NDRTEDEQFN DEKTYLVKQI RDLKRPAQQE A
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