Putative RNA-binding protein Luc7-like 2 (LUC7L2)

About Putative RNA-binding protein Luc7-like 2

Putative RNA-binding protein Luc7-like 2 (LUC7L2) is a protein from Homo sapiens identified by UniProt accession Q9Y383, 392 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Putative RNA-binding protein Luc7-like 2
UniProt accession	Q9Y383
Gene	LUC7L2
Organism	Homo sapiens
Length	392 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

Usher syndrome · score 0.27
neurodegenerative disease · score 0.18
reticulocyte count · score 0.17
reticulocyte measurement · score 0.11
BMI-adjusted waist circumference · score 0.10
glioblastoma multiforme · score 0.03
myeloid neoplasm · score 0.01
Abnormal sperm morphology · score 0.01
myelodysplastic syndrome · score 0.01
head and neck squamous cell carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y383-F1	alphafold	PREDICTED	66.33	—

Amino-acid sequence (392 residues)

MSAQAQMRAM LDQLMGTSRD GDTTRQRIKF SDDRVCKSHL LNCCPHDVLS GTRMDLGECL KVHDLALRAD YEIASKEQDF FFELDAMDHL QSFIADCDRR TEVAKKRLAE TQEEISAEVA AKAERVHELN EEIGKLLAKV EQLGAEGNVE ESQKVMDEVE KARAKKREAE EVYRNSMPAS SFQQQKLRVC EVCSAYLGLH DNDRRLADHF GGKLHLGFIE IREKLEELKR VVAEKQEKRN QERLKRREER EREEREKLRR SRSHSKNPKR SRSREHRRHR SRSMSRERKR RTRSKSREKR HRHRSRSSSR SRSRSHQRSR HSSRDRSRER SKRRSSKERF RDQDLASCDR DRSSRDRSPR DRDRKDKKRS YESANGRSED RRSSEEREAG EI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards