Palmitoyltransferase ZDHHC9 (ZDHHC9)

About Palmitoyltransferase ZDHHC9

Palmitoyltransferase ZDHHC9 (ZDHHC9) is a protein from Homo sapiens identified by UniProt accession Q9Y397, 364 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.

Target properties

Protein name	Palmitoyltransferase ZDHHC9
UniProt accession	Q9Y397
Gene	ZDHHC9
Organism	Homo sapiens
Length	364 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (87)

Diseases linked to this target (Open Targets).

syndromic X-linked intellectual disability Raymond type · score 0.77
genetic disorder · score 0.48
Intellectual disability · score 0.46
COVID-19 · score 0.37
X-linked intellectual disability with marfanoid habitus · score 0.37
epilepsy · score 0.37
neurodegenerative disease · score 0.23
Neurodevelopmental disorder · score 0.12
Neurodevelopmental abnormality · score 0.11
neoplasm · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y397-F1	alphafold	PREDICTED	84.30	—

Amino-acid sequence (364 residues)

MSVMVVRKKV TRKWEKLPGR NTFCCDGRVM MARQKGIFYL TLFLILGTCT LFFAFECRYL AVQLSPAIPV FAAMLFLFSM ATLLRTSFSD PGVIPRALPD EAAFIEMEIE ATNGAVPQGQ RPPPRIKNFQ INNQIVKLKY CYTCKIFRPP RASHCSICDN CVERFDHHCP WVGNCVGKRN YRYFYLFILS LSLLTIYVFA FNIVYVALKS LKIGFLETLK ETPGTVLEVL ICFFTLWSVV GLTGFHTFLV ALNQTTNEDI KGSWTGKNRV QNPYSHGNIV KNCCEVLCGP LPPSVLDRRG ILPLEESGSR PPSTQETSSS LLPQSPAPTE HLNSNEMPED SSTPEEMPPP EPPEPPQEAA EAEK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards