Small ribosomal subunit protein uS2m (MRPS2)

About Small ribosomal subunit protein uS2m

Small ribosomal subunit protein uS2m (MRPS2) is a protein from Homo sapiens identified by UniProt accession Q9Y399, 296 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.

Target properties

Protein name	Small ribosomal subunit protein uS2m
UniProt accession	Q9Y399
Gene	MRPS2
Organism	Homo sapiens
Length	296 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (26)

Diseases linked to this target (Open Targets).

combined oxidative phosphorylation deficiency 36 · score 0.71
urate measurement · score 0.03
bone density · score 0.03
parental longevity · score 0.02
gut microbiome measurement · score 0.02
Hypoglycemia · score 0.02
papillary thyroid carcinoma · score 0.01
hepatocellular carcinoma · score 0.01
major depressive disorder · score 0.01
hyperinsulinemic hypoglycemia, familial, 4 · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y399-F1	alphafold	PREDICTED	82.31	—

Amino-acid sequence (296 residues)

MATSSAALPR ILGAGARAPS RWLGFLGKAT PRPARPSRRT LGSATALMIR ESEDSTDFND KILNEPLKHS DFFNVKELFS VRSLFDARVH LGHKAGCRHR FMEPYIFGSR LDHDIIDLEQ TATHLQLALN FTAHMAYRKG IILFISRNRQ FSYLIENMAR DCGEYAHTRY FRGGMLTNAR LLFGPTVRLP DLIIFLHTLN NIFEPHVAVR DAAKMNIPTV GIVDTNCNPC LITYPVPGND DSPLAVHLYC RLFQTAITRA KEKRQQVEAL YRLQGQKEPG DQGPAHPPGA DMSHSL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards