About Serine-threonine kinase receptor-associated protein
Serine-threonine kinase receptor-associated protein (STRAP) is a protein
from Homo sapiens identified by UniProt accession
Q9Y3F4, 350 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Serine-threonine kinase receptor-associated protein |
|---|
| UniProt accession | Q9Y3F4 |
|---|
| Gene | STRAP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 350 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- neuroblastoma · score 0.08
- neoplasm · score 0.08
- cancer · score 0.04
- glaucoma · score 0.04
- Systemic lupus erythematosus · score 0.03
- mental process · score 0.03
- alcohol drinking · score 0.03
- hepatocellular carcinoma · score 0.03
- intrahepatic cholangiocarcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y3F4-F1 | alphafold | PREDICTED | 89.59 | — |
Amino-acid sequence (350 residues)
MAMRQTPLTC SGHTRPVVDL AFSGITPYGY FLISACKDGK PMLRQGDTGD WIGTFLGHKG AVWGATLNKD ATKAATAAAD FTAKVWDAVS GDELMTLAHK HIVKTVDFTQ DSNYLLTGGQ DKLLRIYDLN KPEAEPKEIS GHTSGIKKAL WCSEDKQILS ADDKTVRLWD HATMTEVKSL NFNMSVSSME YIPEGEILVI TYGRSIAFHS AVSLDPIKSF EAPATINSAS LHPEKEFLVA GGEDFKLYKY DYNSGEELES YKGHFGPIHC VRFSPDGELY ASGSEDGTLR LWQTVVGKTY GLWKCVLPEE DSGELAKPKI GFPETTEEEL EEIASENSDC IFPSAPDVKA
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