About C2 domain-containing protein 2
C2 domain-containing protein 2 (C2CD2) is a protein
from Homo sapiens identified by UniProt accession
Q9Y426, 696 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | C2 domain-containing protein 2 |
|---|
| UniProt accession | Q9Y426 |
|---|
| Gene | C2CD2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 696 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- platelet count · score 0.38
- platelet crit · score 0.31
- testosterone measurement · score 0.31
- myeloid white cell count · score 0.09
- hypoparathyroidism, familial isolated, 2 · score 0.06
- Primary hypomagnesemia with secondary hypocalcemia · score 0.06
- pseudohypoparathyroidism type 2 · score 0.05
- 22q11.2 deletion syndrome · score 0.05
- Familial isolated hypoparathyroidism · score 0.04
- familial isolated hyperparathyroidism · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y426-F1 | alphafold | PREDICTED | 62.00 | — |
Amino-acid sequence (696 residues)
MAMARLGSWL GEAQWLALVS LFVAALATVG LYLAQWALAR ARPQPQRRAV EPGEGPRPGS DALLSWILTL GSWRSQWQAA WVTALNEEAE RKGGPPFLSF EEDPRQQALE LVVQEVSSVL RSAEEKVVVC HVVGQAIQFL VSETPALGAG CRLYDMRLSP FHLQLEFHMK EKREDLQISW SFISVPEMAV NIQPKALGED QVAETSAMSD VLKDILKHLA GSASPSVVLI TKPTTVKEAQ NLQCAASTAQ ESCPPKPPRA HELKLLVRNI HVLLLSEPGA SGHINAVCVV QLNDPVQRFS STLTKNTPDL MWEEEFTFEL NAKSKELHLQ ISEAGRSSEG LLATATVPLD LFKKQPSGPQ SFTLTSGSAC GSSVLGSVTA EFSYMEPGEL KSWPIPPPVP AAKIEKDRTV MPCGTVVTTV TAVKTKPRVD VGRASPLSSD SPVKTPIKVK VIEKDISVQA IACRSAPVSK TLSSSDTELL VLNGSDPVAE VAIRQLSESS KLKLKSPRKK STIIISGISK TSLSQDHDAA LMQGYTASVD STHQEDAPSH PERAAASAPP EEAESAQASL APKPQEDELD SWDLEKEPQA AAWSSQVLLD PDGDELSESS MSVLEPGTAK KHKGGILRKG AKLFFRRRHQ QKDPGMSQSH NDLVFLEQPE GSRRKGITLT RILNKKLLSR HRNKNTMNGA PVEPCT
Explore C2 domain-containing protein 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets