About HBS1-like protein
HBS1-like protein (HBS1L) is a protein
from Homo sapiens identified by UniProt accession
Q9Y450, 684 residues long.
MolForge cross-references it against 0 known binders and
180 disease associations.
Target properties
| Protein name | HBS1-like protein |
|---|
| UniProt accession | Q9Y450 |
|---|
| Gene | HBS1L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 684 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (180)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.52
- mean corpuscular volume · score 0.50
- mean corpuscular hemoglobin concentration · score 0.50
- erythrocyte count · score 0.49
- mean corpuscular hemoglobin · score 0.49
- platelet count · score 0.49
- Red cell distribution width · score 0.48
- reticulocyte measurement · score 0.48
- platelet crit · score 0.47
- red blood cell density measurement · score 0.47
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y450-F1 | alphafold | PREDICTED | 74.03 | — |
Amino-acid sequence (684 residues)
MARHRNVRGY NYDEDFEDDD LYGQSVEDDY CISPSTAAQF IYSRRDKPSV EPVEEYDYED LKESSNSVSN HQLSGFDQAR LYSCLDHMRE VLGDAVPDEI LIEAVLKNKF DVQKALSGVL EQDRVQSLKD KNEATVSTGK IAKGKPVDSQ TSRSESEIVP KVAKMTVSGK KQTMGFEVPG VSSEENGHSF HTPQKGPPIE DAIASSDVLE TASKSANPPH TIQASEEQSS TPAPVKKSGK LRQQIDVKAE LEKRQGGKQL LNLVVIGHVD AGKSTLMGHM LYLLGNINKR TMHKYEQESK KAGKASFAYA WVLDETGEER ERGVTMDVGM TKFETTTKVI TLMDAPGHKD FIPNMITGAA QADVAVLVVD ASRGEFEAGF ETGGQTREHG LLVRSLGVTQ LAVAVNKMDQ VNWQQERFQE ITGKLGHFLK QAGFKESDVG FIPTSGLSGE NLITRSQSSE LTKWYKGLCL LEQIDSFKPP QRSIDKPFRL CVSDVFKDQG SGFCITGKIE AGYIQTGDRL LAMPPNETCT VKGITLHDEP VDWAAAGDHV SLTLVGMDII KINVGCIFCG PKVPIKACTR FRARILIFNI EIPITKGFPV LLHYQTVSEP AVIKRLISVL NKSTGEVTKK KPKFLTKGQN ALVELQTQRP IALELYKDFK ELGRFMLRYG GSTIAAGVVT EIKE
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