About Protein PRRC2C
Protein PRRC2C (PRRC2C) is a protein
from Homo sapiens identified by UniProt accession
Q9Y520, 2896 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | Protein PRRC2C |
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| UniProt accession | Q9Y520 |
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| Gene | PRRC2C |
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| Organism | Homo sapiens |
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| Length | 2896 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (53)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.39
- creatinine measurement · score 0.30
- self reported educational attainment · score 0.29
- body mass index · score 0.28
- urinary albumin to creatinine ratio · score 0.26
- glomerular filtration rate · score 0.26
- cortical surface area measurement · score 0.25
- high density lipoprotein cholesterol measurement · score 0.24
- body height · score 0.24
- brain measurement · score 0.21
3D Structure (9)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Amino-acid sequence (2896 residues)
MSEKSGQSTK AKDGKKYATL SLFNTYKGKS LETQKTTARH GLQSLGKVGI SRRMPPPANL PSLKAENKGN DPNVNIVPKD GTGWASKQEQ HEEEKTPEVP PAQPKPGVAA PPEVAPAPKS WASNKQGGQG DGIQVNSQFQ QEFPSLQAAG DQEKKEKETN DDNYGPGPSL RPPNVACWRD GGKAAGSPSS SDQDEKLPGQ DESTAGTSEQ NDILKVVEKR IACGPPQAKL NGQQAALASQ YRAMMPPYMF QQYPRMTYPP LHGPMRFPPS LSETNKGLRG RGPPPSWASE PERPSILSAS ELKELDKFDN LDAEADEGWA GAQMEVDYTE QLNFSDDDEQ GSNSPKENNS EDQGSKASEN NENKKETDEV SNTKSSSQIP AQPSVAKVPY GKGPSFNQER GTSSHLPPPP KLLAQQHPPP DRQAVPGRPG PFPSKQQVAD EDEIWKQRRR QQSEISAAVE RARKRREEEE RRMEEQRKAA CAEKLKRLDE KLGILEKQPS PEEIRERERE KEREREKELE KEQEQEREKE REKDRERQQE KEKELEKEQE KQREMEKERK QEKEKELERQ KEKEKELQKM KEQEKECELE KEREKLEEKI EPREPNLEPM VEKQESENSC NKEEEPVFTR QDSNRSEKEA TPVVHETEPE SGSQPRPAVL SGYFKQFQKS LPPRFQRQQE QMKQQQWQQQ QQQGVLPQTV PSQPSSSTVP PPPHRPLYQP MQPHPQHLAS MGFDPRWLMM QSYMDPRMMS GRPAMDIPPI HPGMIPPKPL MRRDQMEGSP NSSESFEHIA RSARDHAISL SEPRMLWGSD PYPHAEPQQA TTPKATEEPE DVRSEAALDQ EQITAAYSVE HNQLEAHPKA DFIRESSEAQ VQKFLSRSVE DVRPHHTDAN NQSACFEAPD QKTLSAPQEE RISAVESQPS RKRSVSHGSN HTQKPDEQRS EPSAGIPKVT SRCIDSKEPI ERPEEKPKKE GFIRSSEGPK PEKVYKSKSE TRWGPRPSSN RREEVNDRPV RRSGPIKKPV LRDMKEEREQ RKEKEGEKAE KVTEKVVVKP EKTEKKDLPP PPPPPQPPAP IQPQSVPPPI QPEAEKFPST ETATLAQKPS QDTEKPLEPV STVQVEPAVK TVNQQTMAAP VVKEEKQPEK VISKDLVIER PRPDSRPAVK KESTLPPRTY WKEARERDWF PDQGYRGRGR GEYYSRGRSY RGSYGGRGRG GRGHTRDYPQ YRDNKPRAEH IPSGPLRQRE ESETRSESSD FEVVPKRRRQ RGSETDTDSE IHESASDKDS LSKGKLPKRE ERPENKKPVK PHSSFKPDNH VRIDNRLLEK PYVRDDDKAK PGFLPKGEPT RRGRGGTFRR GGRDPGGRPS RPSTLRRPAY RDNQWNPRQS EVPKPEDGEP PRRHEQFIPI AADKRPPKFE RKFDPARERP RRQRPTRPPR QDKPPRFRRL REREAASKSN EVVAVPTNGT VNNVAQEPVN TLGDISGNKT PDLSNQNSSD QANEEWETAS ESSDFNERRE RDEKKNADLN AQTVVKVGEN VLPPKREIAK RSFSSQRPVD RQNRRGNNGP PKSGRNFSGP RNERRSGPPS KSGKRGPFDD QPAGTTGVDL INGSSAHHQE GVPNGTGQKN SKDSTGKKRE DPKPGPKKPK EKVDALSQFD LNNYASVVII DDHPEVTVIE DPQSNLNDDG FTEVVSKKQQ KRLQDEERRK KEEQVIQVWN KKNANEKGRS QTSKLPPRFA KKQATGIQQA QSSASVPPLA SAPLPPSTSA SVPASTSAPL PATLTPVPAS TSAPVPASTL APVLASTSAP VPASPLAPVS ASASVSASVP ASTSAAAITS SSAPASAPAP TPILASVSTP ASVTILASAS IPILASALAS TSAPTPAPAA SSPAAPVITA PTIPASAPTA SVPLAPASAS APAPAPTPVS APNPAPPAPA QTQAQTHKPV QNPLQTTSQS SKQPPPSIRL PSAQTPNGTD YVASGKSIQT PQSHGTLTAE LWDNKVAPPA VLNDISKKLG PISPPQPPSV SAWNKPLTSF GSAPSSEGAK NGQESGLEIG TDTIQFGAPA SNGNENEVVP VLSEKSADKI PEPKEQRQKQ PRAGPIKAQK LPDLSPVENK EHKPGPIGKE RSLKNRKVKD AQQVEPEGQE KPSPATVRST DPVTTKETKA VSEMSTEIGT MISVSSAEYG TNAKESVTDY TTPSSSLPNT VATNNTKMED TLVNNVPLPN TLPLPKRETI QQSSSLTSVP PTTFSLTFKM ESARKAWENS PNVREKGSPV TSTAPPIATG VSSSASGPST ANYNSFSSAS MPQIPVASVT PTASLSGAGT YTTSSLSTKS TTTSDPPNIC KVKPQQLQTS SLPSASHFSQ LSCMPSLIAQ QQQNPQVYVS QSAAAQIPAF YMDTSHLFNT QHARLAPPSL AQQQGFQPGL SQPTSVQQIP IPIYAPLQGQ HQAQLSLGAG PAVSQAQELF SSSLQPYRSQ PAFMQSSLSQ PSVVLSGTAI HNFPTVQHQE LAKAQSGLAF QQTSNTQPIP ILYEHQLGQA SGLGGSQLID THLLQARANL TQASNLYSGQ VQQPGQTNFY NTAQSPSALQ QVTVPLPASQ LSLPNFGSTG QPLIALPQTL QPPLQHTTPQ AQAQSLSRPA QVSQPFRGLI PAGTQHSMIA TTGKMSEMEL KAFGSGIDIK PGTPPIAGRS TTPTSSPFRA TSTSPNSQSS KMNSIVYQKQ FQSAPATVRM TQPFPTQFAP QILSQPNLVP PLVRAPHTNT FPAPVQRPPM ALASQMPPPL TTGLMSHARL PHVARGPCGS LSGVRGNQAQ AALKAEQDMK AKQRAEVLQS TQRFFSEQQQ SKQIGGGKAQ KVDSDSSKPP ETLTDPPGVC QEKVEEKPPP APSIATKPVR TGPIKPQAIK TEETKS
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