About Actin-binding protein IPP
Actin-binding protein IPP (IPP) is a protein
from Homo sapiens identified by UniProt accession
Q9Y573, 584 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Actin-binding protein IPP |
|---|
| UniProt accession | Q9Y573 |
|---|
| Gene | IPP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 584 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- platelet count · score 0.19
- brain measurement · score 0.18
- cortical surface area measurement · score 0.17
- age-related hearing impairment · score 0.16
- body height · score 0.13
- apolipoprotein A 1 measurement · score 0.12
- total blood protein measurement · score 0.11
- body fat percentage · score 0.10
- mean corpuscular volume · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y573-F1 | alphafold | PREDICTED | 90.06 | — |
Amino-acid sequence (584 residues)
MANEDCPKAA DSPFSSDKHA QLILAQINKM RNGQHFCDVQ LQVGQESFKA HRLVLAASSP YFAALFTGGM KESSKDVVPI LGIEAGIFQI LLDFIYTGIV NIGVNNVQEL IIAADMLQLT EVVHLCCEFL KGQIDPLNCI GIFQFSEQIA CHDLLEFSEN YIHVHFLEVH SGEEFLALTK DQLIKILRSE ELSIEDEYQV FLAAMQWILK DLGKRRKHVV EVLDPIRFPL LPPQRLLKYI EGVSDFNLRV ALQTLLKEYC EVCKSPKENK FCSFLQTSKV RPRKKARKYL YAVGGYTRLQ GGRWSDSRAL SCVERFDTFS QYWTTVSSLH QARSGLGVTV LGGMVYAIGG EKDSMIFDCT ECYDPVTKQW TTVASMNHPR CGLGVCVCYG AIYALGGWVG AEIGNTIERF DPDENKWEVV GNMAVSRYYF GCCEMQGLIY VIGGISNEGI ELRSFEVYDP LSKRWSPLPP MGTRRAYLGV AALNDCIYSV GGWNETQDAL HTVEKYSFEE EKWVEVASMK VPRAGMCVVA VNGLLYVSGG RSSSHDFLAP GTLDSVEVYN PHSDTWTEIG NMITSRCEGG VAVL
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