E3 ubiquitin-protein ligase TRIM17 (TRIM17)

Homo sapiens — UniProt Q9Y577

Gene: TRIM17Homo sapiensSwissProt reviewed

About E3 ubiquitin-protein ligase TRIM17

E3 ubiquitin-protein ligase TRIM17 (TRIM17) is a protein from Homo sapiens identified by UniProt accession Q9Y577, 477 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.

Target properties

Protein nameE3 ubiquitin-protein ligase TRIM17
UniProt accessionQ9Y577
GeneTRIM17
OrganismHomo sapiens
Length477 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y577-F1alphafoldPREDICTED85.75—

Amino-acid sequence (477 residues)

MEAVELARKL QEEATCSICL DYFTDPVMTT CGHNFCRACI QLSWEKARGK KGRRKRKGSF PCPECREMSP QRNLLPNRLL TKVAEMAQQH PGLQKQDLCQ EHHEPLKLFC QKDQSPICVV CRESREHRLH RVLPAEEAVQ GYKLKLEEDM EYLREQITRT GNLQAREEQS LAEWQGKVKE RRERIVLEFE KMNLYLVEEE QRLLQALETE EEETASRLRE SVACLDRQGH SLELLLLQLE ERSTQGPLQM LQDMKEPLSR KNNVSVQCPE VAPPTRPRTV CRVPGQIEVL RGFLEDVVPD ATSAYPYLLL YESRQRRYLG SSPEGSGFCS KDRFVAYPCA VGQTAFSSGR HYWEVGMNIT GDALWALGVC RDNVSRKDRV PKCPENGFWV VQLSKGTKYL STFSALTPVM LMEPPSHMGI FLDFEAGEVS FYSVSDGSHL HTYSQATFPG PLQPFFCLGA PKSGQMVIST VTMWVKG

Explore E3 ubiquitin-protein ligase TRIM17 with MolForge

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Quick facts

UniProtQ9Y577
GeneTRIM17
OrganismHomo sapiens
Length477
Binders0
Diseases46
View on UniProt