RNA-binding protein 7 (RBM7)

About RNA-binding protein 7

RNA-binding protein 7 (RBM7) is a protein from Homo sapiens identified by UniProt accession Q9Y580, 266 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	RNA-binding protein 7
UniProt accession	Q9Y580
Gene	RBM7
Organism	Homo sapiens
Length	266 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.42
IGF-1 measurement · score 0.18
ulcerative colitis · score 0.05
Senior-Boichis syndrome · score 0.05
interstitial lung disease · score 0.04
hepatorenocardiac degenerative fibrosis · score 0.04
neoplasm · score 0.04
pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 9 · score 0.04
nephronophthisis 3 · score 0.04
immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y580-F1	alphafold	PREDICTED	65.22	—

Amino-acid sequence (266 residues)

MGAAAAEADR TLFVGNLETK VTEELLFELF HQAGPVIKVK IPKDKDGKPK QFAFVNFKHE VSVPYAMNLL NGIKLYGRPI KIQFRSGSSH APQDVSLSYP QHHVGNSSPT STSPSRYERT MDNMTSSAQI IQRSFSSPEN FQRQAVMNSA LRQMSYGGKF GSSPLDQSGF SPSVQSHSHS FNQSSSSQWR QGTPSSQRKV RMNSYPYLAD RHYSREQRYT DHGSDHHYRG KRDDFFYEDR NHDDWSHDYD NRRDSSRDGK WRSSRH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards