About Insulin-like peptide INSL6
Insulin-like peptide INSL6 (INSL6) is a protein
from Homo sapiens identified by UniProt accession
Q9Y581, 213 residues long.
MolForge cross-references it against 0 known binders and
150 disease associations.
Target properties
| Protein name | Insulin-like peptide INSL6 |
|---|
| UniProt accession | Q9Y581 |
|---|
| Gene | INSL6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 213 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (150)
Diseases linked to this target (Open Targets).
- platelet count · score 0.50
- platelet crit · score 0.28
- IGF-1 measurement · score 0.26
- eosinophil percentage of leukocytes · score 0.24
- polycythemia vera · score 0.22
- myeloproliferative disorder · score 0.19
- hepatic vein thrombosis · score 0.18
- erythrocyte count · score 0.17
- essential thrombocythemia · score 0.16
- eosinophilic esophagitis · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9Y581-F1 | alphafold | PREDICTED | 54.74 | — |
Amino-acid sequence (213 residues)
MPRLLRLSLL WLGLLLVRFS RELSDISSAR KLCGRYLVKE IEKLCGHANW SQFRFEEETP FSRLIAQASE KVEAYSPYQF ESPQTASPAR GRGTNPVSTS WEEAVNSWEM QSLPEYKDKK GYSPLGKTRE FSSSHNINVY IHENAKFQKK RRNKIKTLSN LFWGHHPQRK RRGYSEKCCL TGCTKEELSI ACLPYIDFKR LKEKRSSLVT KIY
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