Chondrosarcoma-associated gene 2/3 protein (CSAG2)

About Chondrosarcoma-associated gene 2/3 protein

Chondrosarcoma-associated gene 2/3 protein (CSAG2) is a protein from Homo sapiens identified by UniProt accession Q9Y5P2, 127 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Chondrosarcoma-associated gene 2/3 protein
UniProt accession	Q9Y5P2
Gene	CSAG2
Organism	Homo sapiens
Length	127 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

hepatocellular carcinoma · score 0.03
lung carcinoma · score 0.02
Ataxia-telangiectasia · score 0.01
chondrosarcoma · score 0.01
non-small cell lung carcinoma · score 0.01
cutaneous lupus erythematosus · score 0.01
neoplasm · score 0.01
melanoma · score 0.00
ovarian carcinoma · score 0.00
bladder transitional cell carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9Y5P2-F1	alphafold	PREDICTED	56.48	—

Amino-acid sequence (127 residues)

MWMGLIQLVE GVKRKDQGFL EKEFYHKTNI KMRCEFLACW PAFTVLGEAW RDQVDWSRLL RDAGLVKMSR KPRASSPLSN NHPPTPKRRG SGRHPLNPGP EALSKFPRQP GREKGPIKEV PGTKGSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards